Active Ingredient Aflibercept

Active Ingredient Details

What is Aflibercept?

has antiangiogenic activity; consists of the second and third Ig domains of VEGFR1 and VEGFR2, respectively, fusion to the Fc region of IgG1; putative antineoplastic agent that binds all VEGF-A isoforms; possible medicine for eye disorders

What is the usage for Aflibercept?

Aflibercept is used to treat certain serious eye conditions (such as wet age-related macular degeneration, diabetic retinopathy/macular edema, macular edema following retinal vein occlusion). This medication can help preserve vision and prevent blindness. Aflibercept belongs to a class of drugs known as growth factor inhibitors. It works by slowing the growth of abnormal new blood vessels in the eye and decreasing leakage from these blood vessels.

How many products in the NDC database contain Aflibercept?

The NDC database has 15 products with the active ingredient Aflibercept. The following table lists all the products that have this active ingredient.

NDC Products with Aflibercept

NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
0024-5840	Proprietary Name: Zaltrap	Ziv-aflibercept	Solution, Concentrate	Intravenous	Sanofi-aventis U.s. Llc	ACTIVE
0024-5841	Proprietary Name: Zaltrap	Ziv-aflibercept	Solution, Concentrate	Intravenous	Sanofi-aventis U.s. Llc	ACTIVE
55513-056	Proprietary Name: Pavblu	Aflibercept-ayyh	Injection, Solution	Intravitreal	Amgen, Inc	ACTIVE
55513-065	Proprietary Name: Pavblu	Aflibercept-ayyh	Injection, Solution	Intravitreal	Amgen, Inc	ACTIVE
61434-007	Proprietary Name:	Aflibercept	Injection, Solution		Catalent Indiana, Llc	ACTIVE
61434-062	Proprietary Name:	Aflibercept	Injection, Solution		Catalent Indiana, Llc	ACTIVE
61434-077	Proprietary Name:	Aflibercept	Injection, Solution		Catalent Indiana, Llc	ACTIVE
61755-005	Proprietary Name: Eylea	Aflibercept	Injection, Solution	Intravitreal	Regeneron Pharmaceuticals, Inc.	ACTIVE
61755-050	Proprietary Name: Eylea Hd	Aflibercept	Injection, Solution	Intravitreal	Regeneron Pharmaceuticals, Inc	ACTIVE
61755-051	Proprietary Name: Eylea Hd	Aflibercept	Injection, Solution	Intravitreal	Regeneron Pharmaceuticals, Inc	ACTIVE
61755-905	Proprietary Name:	Aflibercept	Injection, Solution		Regeneron Pharmaceuticals, Inc.	ACTIVE
61755-930	Proprietary Name:	Aflibercept	Injection, Solution		Regeneron Pharmaceuticals, Inc	ACTIVE
61755-950	Proprietary Name:	Aflibercept	Injection, Solution		Regeneron Pharmaceuticals, Inc.	ACTIVE
83012-052	Proprietary Name:	Aflibercept	Liquid		Boehringer Ingelheim Fremont, Inc.	ACTIVE
83277-004	Proprietary Name:	Aflibercept	Solution		Agc Biologics, Inc.	ACTIVE