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Active Ingredient Methotrexate

Active Ingredient Details

What is Methotrexate?

An antineoplastic antimetabolite with immunosuppressant properties. It is an inhibitor of TETRAHYDROFOLATE DEHYDROGENASE and prevents the formation of tetrahydrofolate, necessary for synthesis of thymidylate, an essential component of DNA.

What is the usage for Methotrexate?

Methotrexate is used to treat certain types of cancer or to control severe psoriasis or rheumatoid arthritis that has not responded to other treatments. It may also be used to control juvenile rheumatoid arthritis. Methotrexate belongs to a class of drugs known as antimetabolites. It works by slowing or stopping the growth of cancer cells and suppressing the immune system. Early treatment of rheumatoid arthritis with more aggressive therapy such as methotrexate helps to reduce further joint damage and to preserve joint function.

How many products in the NDC database contain Methotrexate?

The NDC database has 27 products with the active ingredient Methotrexate. The following table lists all the products that have this active ingredient.

NDC Products with Methotrexate

NDC Proprietary Name Non-Proprietary Name Dosage Form Route Name Company Name Status
0143-9367Proprietary Name: Methotrexate MethotrexateInjection, Powder, Lyophilized, For SolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9516Proprietary Name: Methotrexate MethotrexateSolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9517Proprietary Name: Methotrexate MethotrexateSolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9518Proprietary Name: Methotrexate MethotrexateSolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9519Proprietary Name: Methotrexate MethotrexateSolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9830Proprietary Name: Methotrexate MethotrexateInjection, Powder, Lyophilized, For SolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0904-7141Proprietary Name: Methotrexate MethotrexateTabletOralMajor PharmaceuticalsACTIVE
12780-0491Proprietary Name: MethotrexatePowderFermion OyACTIVE
16729-277Proprietary Name: Methotrexate MethotrexateInjectionIntra-arterial; Intramuscular; Intrathecal; IntravenousAccord Healthcare, Inc.ACTIVE
46014-1023Proprietary Name: MethotrexatePowderExcella Gmbh & Co. KgACTIVE
46014-1133Proprietary Name: MethotrexatePowderExcella Gmbh & Co. KgACTIVE
49452-4601Proprietary Name: MethotrexatePowderSpectrum Laboratory Products, Inc.ACTIVE
51927-1565Proprietary Name: MethotrexatePowderProfessional Compounding Centers Of America Dba PccaACTIVE
52652-2001Proprietary Name: Xatmep MethotrexateSolutionOralAzurity Pharmaceuticals, Inc.ACTIVE
54436-010Proprietary Name: Otrexup MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-012Proprietary Name: Otrexup MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-015Proprietary Name: Otrexup MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-017Proprietary Name: Otrexup MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-020Proprietary Name: Otrexup MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-022Proprietary Name: Otrexup MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-025Proprietary Name: Otrexup MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
58623-0040Proprietary Name: MethotrexatePowderZhejiang Hisun Pharmaceutical Co., Ltd.ACTIVE
63660-0006Proprietary Name: MethotrexatePowderHuzhou Zhanwang Pharmaceutical Co. LtdACTIVE
68382-775Proprietary Name: Methotrexate MethotrexateTabletOralZydus Pharmaceuticals Usa Inc.ACTIVE
70518-1398Proprietary Name: Methotrexate MethotrexateTabletOralRemedyrepack Inc.ACTIVE
70771-1058Proprietary Name: Methotrexate MethotrexateTabletOralZydus Lifesciences LimitedACTIVE
81927-204Proprietary Name: Jylamvo MethotrexateSolutionOralShorla Oncology Inc.ACTIVE
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