Active Ingredient Tolcapone
Active Ingredient Details
What is Tolcapone?
A benzophenone and nitrophenol compound that acts as an inhibitor of CATECHOL O-METHYLTRANSFERASE, an enzyme involved in the metabolism of DOPAMINE and LEVODOPA. It is used in the treatment of PARKINSON DISEASE in patients for whom levodopa is ineffective or contraindicated.
What is the usage for Tolcapone?
This medication is used with other medications (levodopa/carbidopa) to treat Parkinson's disease. Tolcapone belongs to a class of drugs known as COMT inhibitors. Many people taking levodopa for Parkinson's have problems with the effects of the levodopa wearing off between scheduled doses, causing symptoms to return or worsen. Tolcapone blocks a certain natural substance (COMT enzyme) that breaks down levodopa in the body. This effect allows the levodopa to last longer in the system so that it doesn't wear off before the next dose.
How many products in the NDC database contain Tolcapone?
The NDC database has 6 products with the active ingredient Tolcapone. The following table lists all the products that have this active ingredient.
NDC Products with Tolcapone
| NDC | Proprietary Name | Non-Proprietary Name | Dosage Form | Route Name | Company Name | Status | |
|---|---|---|---|---|---|---|---|
| 0187-0938 | Proprietary Name: Tasmar | Tolcapone | Tablet, Film Coated | Oral | Bausch Health Us Llc | ACTIVE | |
| 17511-119 | Proprietary Name: | Tolcapone | Powder | Cohance Lifesciences Limited | ACTIVE | ||
| 50742-193 | Proprietary Name: Tolcapone | Tolcapone | Tablet | Oral | Ingenus Pharmaceuticals, Llc | ACTIVE | |
| 65085-0032 | Proprietary Name: | Tolcapone | Powder | Piramal Pharma Limited | ACTIVE | ||
| 68682-938 | Proprietary Name: Tolcapone | Tolcapone | Tablet, Film Coated | Oral | Oceanside Pharmaceuticals | ACTIVE | |
| 76438-001 | Proprietary Name: | Tolcapone | Powder | Anthem Biosciences Pvt. Ltd | ACTIVE |