List of products in the National Drug Code with proprietary name . Canagliflozin is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Canagliflozin is also used by people with type 2 diabetes and heart disease to lower the risk of death from heart attack or stroke. Canagliflozin is also used by people with type 2 diabetes and kidney disease to lower the risk of dialysis, death from heart disease, and the need to go to the hospital for heart failure. Canagliflozin works by increasing the removal of sugar by your kidneys.