List of products in the National Drug Code with proprietary name . Rosiglitazone is used with a proper diet and exercise program to control high blood sugar in people with type 2 diabetes. Controlling high blood sugar helps prevent kidney damage, blindness, nerve problems, loss of limbs, and sexual function problems. Proper control of diabetes may also lessen your risk of a heart attack or stroke. Rosiglitazone belongs to the class of drugs known as glitazones. It lowers blood sugar by helping to restore your body's proper response to insulin.