Doxycycline Hyclate
Pricing Report NDC 0378-0167-05

Latest NADAC: $0.14112 per EA · Effective Feb 23, 2022 · Est. package price $70.56 (500 EA)

Current Package Pricing Information

This product is EXCLUDED from the official NDC directory because the listing data was discontinued by the firm.

The latest wholesale acquisition cost for Doxycycline Hyclate (NDC 0378-0167-05) is $0.14112 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Feb 23, 2022.

As a provided by Mylan Pharmaceuticals Inc., this medication is distributed in a 500 TABLET, FILM COATED in 1 BOTTLE, PLASTIC configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.14112
Per EA

Effective Date
Feb 23, 2022
Billable Units
500 EA
Estimated Package Price
$70.56
Data Status
As of Mar 02, 2022
C/I - Chain or Independent Pharmacy
Package NDC
Description
500 TABLET, FILM COATED in 1 BOTTLE, PLASTIC
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Apr 2015, the NADAC wholesale price for (NDC ) has moved within a range of $0.10670 to $2.08156 per EA. Over this 10 years and 7 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.1067 - $2.0816
Market Volatility
1,850.85% Variance
Latest Trend
1.63%

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Nov 19, 2025 $0.12125 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 22, 2025 $0.11930 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 17, 2025 $0.12060 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Aug 20, 2025 $0.12257 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $0.12317 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $0.12619 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $0.12809 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $0.12859 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $0.12511 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $0.11790 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $0.10787 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 01, 2025 $0.10670 EAC/I - Chain or Independent PharmacyCode 1G - Generic

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 4: The NADAC was carried forward from the previous file.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: October 07, 2026