Tretinoin
Pricing Report NDC 0378-8092-45
View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends
Current Package Pricing Information
This product is EXCLUDED from the official NDC directory because the listing data was discontinued by the firm.
The latest wholesale acquisition cost for Tretinoin (NDC 0378-8092-45) is $6.87640 per GM. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Aug 20, 2025.
As a provided by Mylan Pharmaceuticals Inc., this medication is distributed in a 1 TUBE in 1 CARTON / 45 g in 1 TUBE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.
NADAC Pricing Summary
NADAC pricing snapshot for this package NDC
Acquisition Cost $6.87640 Per GM
Pricing Unit
Effective Date
Aug 20, 2025
Billable Units
45 GM
Estimated Package Price
$309.44
Data Status
As of Aug 20, 2025
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.
The NADAC was calculated based on package size.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.
The NADAC was calculated based on package size.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.
Historical Pricing Trends & Acquisition Cost Benchmarks
Since Oct 2019, the NADAC wholesale price for (NDC ) has moved within a range of $5.69178 to $11.45240 per GM. Over this 5 years and 10 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.
Price Range
$7.3216 - $11.4524
$7.3216 - $11.4524
Market Volatility
56.42% Variance
56.42% Variance
Latest Trend
2.79%
2.79%
| Date | Unit Price | Unit | Source | Method | Rate |
|---|---|---|---|---|---|
| Aug 20, 2025 | $10.11271 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Aug 20, 2025 | $6.87640 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Aug 20, 2025 | $9.48540 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Jul 23, 2025 | $9.83786 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Jul 23, 2025 | $6.67189 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Jul 23, 2025 | $9.19762 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Jun 18, 2025 | $9.28779 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Jun 18, 2025 | $6.77725 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Jun 18, 2025 | $9.19762 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| May 21, 2025 | $8.85679 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| May 21, 2025 | $6.82939 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| May 21, 2025 | $8.42638 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Apr 23, 2025 | $8.44364 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Apr 23, 2025 | $6.89621 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Apr 23, 2025 | $8.07903 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Mar 19, 2025 | $8.31772 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Mar 19, 2025 | $6.90309 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Mar 19, 2025 | $8.18991 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Feb 19, 2025 | $8.13763 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Feb 19, 2025 | $6.55662 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Feb 19, 2025 | $7.96388 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Jan 22, 2025 | $7.93651 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Jan 22, 2025 | $6.34688 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Jan 22, 2025 | $7.83692 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Dec 18, 2024 | $7.84334 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Dec 18, 2024 | $5.97401 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Dec 18, 2024 | $7.63433 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Nov 20, 2024 | $7.64346 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Nov 20, 2024 | $6.11569 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Nov 20, 2024 | $7.83424 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Oct 23, 2024 | $7.96731 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Oct 23, 2024 | $5.84281 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Oct 23, 2024 | $7.80392 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Sep 18, 2024 | $8.35586 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Sep 18, 2024 | $5.69178 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Sep 18, 2024 | $7.48073 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Aug 21, 2024 | $8.43063 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Aug 21, 2024 | $5.69178 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Aug 21, 2024 | $7.18949 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Jul 17, 2024 | $8.43063 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Jul 17, 2024 | $5.72931 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Jul 17, 2024 | $7.39504 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Jun 19, 2024 | $9.09455 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Jun 19, 2024 | $6.47827 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Jun 19, 2024 | $8.02260 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| May 22, 2024 | $8.90260 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| May 22, 2024 | $6.46443 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| May 22, 2024 | $7.90435 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Apr 17, 2024 | $10.28023 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Apr 17, 2024 | $6.60453 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Apr 17, 2024 | $7.99082 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| May 17, 2023 | $11.45240 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| May 17, 2023 | $11.45240 | GM | C/I - Chain or Independent Pharmacy | Code 4, 5, 6 | G - Generic |
| Aug 17, 2022 | $7.32180 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Aug 17, 2022 | $7.32180 | GM | C/I - Chain or Independent Pharmacy | Code 4, 5, 6 | G - Generic |
| Sep 23, 2020 | $7.32156 | GM | C/I - Chain or Independent Pharmacy | Code 1, 5, 6 | G - Generic |
| Sep 23, 2020 | $7.32156 | GM | C/I - Chain or Independent Pharmacy | Code 4, 5, 6 | G - Generic |
| Oct 09, 2019 | $7.93267 | GM | C/I - Chain or Independent Pharmacy | Code 4, 5, 6 | G - Generic |
Pricing Methodology Legend
- Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
- Code 4: The NADAC was carried forward from the previous file.
- Code 5: The NADAC was calculated based on package size.
- Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.
Understanding NADAC Pricing Data
The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.
Important Price Distinction:
The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.
NADAC Pricing Data Last Updated on: July 08, 2026
