Estrace
Pricing Report NDC 0430-0721-24

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends

Current Package Pricing Information

This product is EXCLUDED from the official NDC directory because the listing data was discontinued by the firm.

The latest wholesale acquisition cost for Estrace (NDC 0430-0721-24) is $5.20092 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Mar 19, 2025.

As a provided by Allergan, Inc., this medication is distributed in a 100 TABLET in 1 BOTTLE configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$5.20092
Per EA

Effective Date
Mar 19, 2025
Billable Units
100 EA
Estimated Package Price
$520.09
Data Status
As of Nov 19, 2025
C/I - Chain or Independent Pharmacy
B-ANDA - Abbreviated New Drug Application
Package NDC
Description
100 TABLET in 1 BOTTLE
Generic Benchmark
The generic equivalent rate is $0.07036 (Effective: Nov 19, 2025)
Pricing Methodology Explanation
The NADAC was carried forward from the previous file.
The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Sep 2013, the NADAC wholesale price for (NDC ) has moved within a range of $2.41710 to $5.25678 per EA. Over this 11 years and 6 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$2.4171 - $5.2568
Market Volatility
117.48% Variance
Latest Trend
No Change
Date Unit Price Unit Source Method Rate
Mar 19, 2025 $5.20092 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Mar 19, 2025 $5.20092 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Mar 19, 2025 $5.20092 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Mar 19, 2025 $5.20092 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Mar 19, 2025 $5.20092 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Mar 19, 2025 $5.20092 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Mar 19, 2025 $5.20092 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Mar 19, 2025 $5.20092 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Mar 19, 2025 $5.20092 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Feb 19, 2025 $5.20092 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Jan 22, 2025 $5.20092 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Dec 18, 2024 $5.20092 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Nov 20, 2024 $5.20172 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Oct 23, 2024 $5.19140 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Sep 18, 2024 $5.19140 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Aug 21, 2024 $5.19140 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Jul 17, 2024 $5.19480 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Jul 17, 2024 $5.19480 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Jun 19, 2024 $5.19480 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Jun 19, 2024 $5.19480 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
May 22, 2024 $5.19480 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Apr 17, 2024 $5.20433 EAC/I - Chain or Independent PharmacyCode 1, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2019 $5.25678 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2019 $5.25678 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2019 $5.25678 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2019 $5.25678 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2019 $5.25678 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2019 $5.25678 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2019 $5.25678 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2019 $5.25678 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2019 $5.25678 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2019 $5.25678 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2019 $5.25678 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2019 $5.25678 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2019 $5.25678 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2018 $5.01123 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2018 $5.01123 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2018 $5.01123 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2018 $5.01123 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2018 $5.01123 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2018 $5.01123 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2018 $5.01123 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2018 $5.01123 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2018 $5.01123 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2018 $5.01123 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2018 $5.01123 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2018 $5.01123 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2018 $5.01123 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2017 $4.57651 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2017 $4.57651 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2017 $4.57651 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2017 $4.57651 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2017 $4.57651 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2017 $4.57651 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2017 $4.57651 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2017 $4.57651 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2017 $4.57651 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2017 $4.57651 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2017 $4.57651 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2017 $4.57651 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2017 $4.57651 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jul 01, 2016 $4.19867 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jul 01, 2016 $4.19867 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jul 01, 2016 $4.19867 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jul 01, 2016 $4.19867 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jul 01, 2016 $4.19867 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jul 01, 2016 $4.19867 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jul 01, 2016 $4.19867 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2016 $3.85199 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2016 $3.85199 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2016 $3.85199 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2016 $3.85199 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2016 $3.85199 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2016 $3.85199 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 01, 2016 $3.85199 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jul 01, 2015 $3.56662 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jul 01, 2015 $3.56662 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jul 01, 2015 $3.56662 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jul 01, 2015 $3.56662 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jul 01, 2015 $3.56662 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jul 01, 2015 $3.56662 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Oct 01, 2014 $3.10141 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Oct 01, 2014 $3.10141 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Oct 01, 2014 $3.10141 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Oct 01, 2014 $3.10141 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Oct 01, 2014 $3.10141 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Oct 01, 2014 $3.10141 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Oct 01, 2014 $3.10141 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Oct 01, 2014 $3.10141 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Oct 01, 2014 $3.10141 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Oct 01, 2014 $3.10141 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 28, 2014 $2.58451 EAC/I - Chain or Independent PharmacyCode 2, 6B-ANDA - Abbreviated New Drug Application
Jan 28, 2014 $2.58451 EAC/I - Chain or Independent PharmacyCode 3, 6B-ANDA - Abbreviated New Drug Application
Jan 28, 2014 $2.58451 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 28, 2014 $2.58451 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 28, 2014 $2.58451 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 28, 2014 $2.58451 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 28, 2014 $2.58451 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 28, 2014 $2.58451 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Jan 28, 2014 $2.58451 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Sep 19, 2013 $2.41710 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Sep 19, 2013 $2.41710 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application
Sep 19, 2013 $2.41710 EAC/I - Chain or Independent PharmacyCode 4, 6B-ANDA - Abbreviated New Drug Application

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 6: The CMS Covered Outpatient File drug category type of S/I/N (Single Source/Innovator/Non-Innovator) has not been applied. Most S/I drugs with the same strength, dosage form and route of administration were grouped together for the purpose of the NADAC calculation and N drugs were also grouped together. In some cases, however, in calculating a NADAC, the CMS S/I/N designation was not applied when the state Medicaid brand or generic payment practices for these drugs generally differed from the CMS Covered Outpatient File designation.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.


Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026