Methotrexate
Pricing Report NDC 50268-527-15

Latest NADAC: $0.16944 per EA · Effective Aug 20, 2025 · Est. package price $8.47 (50 EA)
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

This product is EXCLUDED from the official NDC directory because the listing data was discontinued by the firm.

The latest wholesale acquisition cost for Methotrexate (NDC 50268-527-15) is $0.16944 per EA. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Aug 20, 2025.

As a provided by Avpak, this medication is distributed in a 50 BLISTER PACK in 1 BOX / 1 TABLET in 1 BLISTER PACK (50268-527-11) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$0.16944
Per EA

Pricing Unit
Per EA Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Aug 20, 2025
Billable Units
50 EA
Estimated Package Price
$8.47
Data Status
As of Aug 20, 2025
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
G - Generic
Package NDC
50268-527-15
Description
50 BLISTER PACK in 1 BOX / 1 TABLET in 1 BLISTER PACK (50268-527-11)
Pricing Methodology Explanation
The NADAC was calculated using information from the most recently completed pharmacy survey.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Oct 2021, the NADAC wholesale price for (NDC ) has moved within a range of $0.15065 to $0.33567 per EA. Over this 3 years and 10 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$0.1507 - $0.3357
Market Volatility
122.81% Variance
Latest Trend
3.15%

Recent NADAC Price History

DateUnit PriceUnitSourceMethodRate
Aug 20, 2025 $0.16944 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jul 23, 2025 $0.16427 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jun 18, 2025 $0.16376 EAC/I - Chain or Independent PharmacyCode 1G - Generic
May 21, 2025 $0.16088 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Apr 23, 2025 $0.16170 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Mar 19, 2025 $0.16106 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Feb 19, 2025 $0.15552 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Jan 22, 2025 $0.15507 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Dec 18, 2024 $0.15834 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Nov 20, 2024 $0.16189 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Oct 23, 2024 $0.17412 EAC/I - Chain or Independent PharmacyCode 1G - Generic
Sep 18, 2024 $0.17536 EAC/I - Chain or Independent PharmacyCode 1G - Generic

Earlier NADAC Price History

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: October 07, 2026