Enbrel
Pricing Report NDC 58406-445-04

View Wholesale Price per Unit, Acquisition Costs, and Historic Pricing Trends
Table of Contents
  1. Current Pricing Information
  2. Pricing History

Current Package Pricing Information

This product is EXCLUDED from the official NDC directory because the listing data was discontinued by the firm.

The latest wholesale acquisition cost for Enbrel (NDC 58406-445-04) is $1381.77087 per ML. This benchmark price is based on the National Average Drug Acquisition Cost (NADAC) and has been effective since Jan 17, 2020.

As a provided by Immunex Corporation, this medication is distributed in a 4 SYRINGE in 1 CARTON / 1 mL in 1 SYRINGE (58406-445-01) configuration. The pricing data is derived from C/I - Chain or Independent Pharmacy surveys, reflecting the actual invoice prices paid by community pharmacies to drug wholesalers.

NADAC Pricing Summary

NADAC pricing snapshot for this package NDC

Acquisition Cost
$1,381.77087
Per ML

Pricing Unit
Per ML Pricing Unit
Indicates the billing unit (ML, GM or EA).
Effective Date
Jan 17, 2020
Data Status
As of Jan 13, 2021
Pharmacy Source Pharmacy Type Indicator
Data collected from Chain/Independent pharmacy surveys.
C/I - Chain or Independent Pharmacy
Rate Classification Classification for Rate Setting
Indicates if the NDC is Brand (B) or Generic (G).
B - Brand
Package NDC
58406-445-04
Description
4 SYRINGE in 1 CARTON / 1 mL in 1 SYRINGE (58406-445-01)
Pricing Methodology Explanation
The NADAC was carried forward from the previous file.
The NADAC was calculated based on package size.

Historical Pricing Trends & Acquisition Cost Benchmarks

Since Jun 2013, the NADAC wholesale price for (NDC ) has moved within a range of $599.83453 to $1,381.77087 per ML. Over this 6 years and 6 months period, the pricing trend reflects the shifting acquisition costs reported by retail and chain pharmacies to the Centers for Medicare and Medicaid Services (CMS). The following interactive chart and historical table detail every recorded price adjustment based on these federal surveys.

Price Range
$599.8345 - $1,381.7709
Market Volatility
130.36% Variance
Latest Trend
7.40%
Date Unit Price Unit Source Method Rate
Jan 17, 2020 $1381.77087 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 17, 2020 $1381.77087 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jun 19, 2019 $1286.56505 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 19, 2019 $1286.56505 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jun 19, 2019 $1286.56505 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 17, 2019 $1283.95917 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 17, 2019 $1283.95917 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 17, 2019 $1283.95917 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Nov 21, 2018 $1209.00110 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Nov 21, 2018 $1209.00110 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 17, 2018 $1209.44845 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 17, 2018 $1209.44845 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 17, 2018 $1209.44845 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Jan 01, 2018 $1205.44560 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jun 21, 2017 $1099.05690 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jun 21, 2017 $1099.05690 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Mar 22, 2017 $1096.51672 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Mar 22, 2017 $1096.51672 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 20, 2017 $1110.70420 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 20, 2017 $1110.70420 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jul 01, 2016 $1024.62542 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jul 01, 2016 $1024.62542 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Dec 23, 2015 $932.32522 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Dec 23, 2015 $932.32522 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Dec 23, 2015 $932.32522 MLC/I - Chain or Independent PharmacyCode 4, 5B - Brand
Sep 02, 2015 $864.07216 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Sep 02, 2015 $864.07216 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
May 01, 2015 $800.80088 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
May 01, 2015 $800.80088 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 21, 2015 $728.66985 MLC/I - Chain or Independent PharmacyCode 1, 5B - Brand
Jan 21, 2015 $728.66985 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Nov 14, 2014 $724.27025 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Nov 14, 2014 $724.27025 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jun 06, 2014 $671.24212 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jun 06, 2014 $671.24212 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 22, 2014 $627.91592 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand
Jan 22, 2014 $627.91592 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jan 02, 2014 $641.21112 MLC/I - Chain or Independent PharmacyCode 3, 5B - Brand
Jun 21, 2013 $599.83453 MLC/I - Chain or Independent PharmacyCode 2, 5B - Brand

Pricing Methodology Legend

  • Code 1: The NADAC was calculated using information from the most recently completed pharmacy survey.
  • Code 2: The average acquisition cost of the most recent survey was within ± 2% of the current NADAC; therefore, the NADAC was carried forward from the previous file.
  • Code 3: The NADAC based on survey data has been adjusted to reflect changes in published pricing, or as a result of an inquiry to the help desk.
  • Code 4: The NADAC was carried forward from the previous file.
  • Code 5: The NADAC was calculated based on package size.

Understanding NADAC Pricing Data

The National Average Drug Acquisition Cost (NADAC) is compiled by the Centers for Medicare and Medicaid Services (CMS). This data is derived from random monthly surveys of more than 60,000 pharmacies across all 50 states.

Important Price Distinction:

The prices listed on this page represent the wholesale invoice price paid by pharmacies to acquire the drug. This is NOT the retail price paid by consumers at the pharmacy counter. Final patient costs typically include pharmacy markups, professional dispensing fees, and insurance adjustments.

NADAC Pricing Data Last Updated on: July 08, 2026