Folic Acid Metabolism Inhibitors [MoA] - N0000000111

Pharmacologic Class Information

Pharmacologic Code N0000000111
Pharmacologic Name Folic Acid Metabolism Inhibitors
Pharmacologic Uses
  • folate analog metabolic inhibitor
Pharmacologic Concept Mechanisms of Action - [MoA]
Pharmacologic Concept Description This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

NDC Products with Folic Acid Metabolism Inhibitors

The following table contains 135 products whose active ingredient are classified under the same pharmacologic class Folic Acid Metabolism Inhibitors [MoA].

NDC Proprietary Name Non-Proprietary Name Dosage Form Route Name Company Name Status
0002-7623Alimta Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousEli Lilly And CompanyACTIVE
0002-7640Alimta Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousEli Lilly And CompanyACTIVE
0054-4550Methotrexate Sodium Non-Proprietary Name: Methotrexate SodiumTabletOralWest-ward Pharmaceuticals Corp.ACTIVE
0054-8550Methotrexate Sodium Non-Proprietary Name: Methotrexate SodiumTabletOralWest-ward Pharmaceuticals Corp.ACTIVE
0143-9367Methotrexate Non-Proprietary Name: MethotrexateInjection, Powder, Lyophilized, For SolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9516Methotrexate Non-Proprietary Name: MethotrexateSolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9517Methotrexate Non-Proprietary Name: MethotrexateSolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9518Methotrexate Non-Proprietary Name: MethotrexateSolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9519Methotrexate Non-Proprietary Name: MethotrexateSolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0143-9830Methotrexate Non-Proprietary Name: MethotrexateInjection, Powder, Lyophilized, For SolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousHikma Pharmaceuticals Usa Inc.ACTIVE
0338-0720Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousBaxter Healthcare CorporationACTIVE
0338-0722Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntraventricularBaxter Healthcare CorporationACTIVE
0378-0014Methotrexate Non-Proprietary Name: MethotrexateTabletOralMylan Pharmaceuticals Inc.ACTIVE
0409-1045Pemetrexed Non-Proprietary Name: PemetrexedInjection, Solution, ConcentrateIntravenousHospira, Inc.ACTIVE
0409-1060Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousHospira, Inc.ACTIVE
0409-1061Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousHospira, Inc.ACTIVE
0409-2188Pemetrexed Non-Proprietary Name: PemetrexedInjection, Solution, ConcentrateIntravenousHospira, Inc.ACTIVE
0409-3532Pemetrexed Non-Proprietary Name: PemetrexedInjection, Solution, ConcentrateIntravenousHospira, Inc.ACTIVE
0480-4514Pemetrexed Non-Proprietary Name: PemetrexedSolution, ConcentrateIntravenousTeva Pharmaceuticals, Inc.ACTIVE
0480-4515Pemetrexed Non-Proprietary Name: PemetrexedSolution, ConcentrateIntravenousTeva Pharmaceuticals, Inc.ACTIVE
0480-4516Pemetrexed Non-Proprietary Name: PemetrexedSolution, ConcentrateIntravenousTeva Pharmaceuticals, Inc.ACTIVE
0555-0572Methotrexate Non-Proprietary Name: MethotrexateTabletOralTeva Pharmaceuticals Usa, Inc.ACTIVE
0703-3671Methotrexate Non-Proprietary Name: MethotrexateInjection, SolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousTeva Parenteral Medicines, Inc.ACTIVE
0703-3675Methotrexate Non-Proprietary Name: MethotrexateInjection, SolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousTeva Parenteral Medicines, Inc.ACTIVE
0703-3678Methotrexate Non-Proprietary Name: MethotrexateInjection, SolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousTeva Parenteral Medicines, Inc.ACTIVE
0781-3518Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, SolutionIntravenousSandoz Inc.ACTIVE
0781-3519Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, SolutionIntravenousSandoz Inc.ACTIVE
0781-3520Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, SolutionIntravenousSandoz Inc.ACTIVE
0904-7141Methotrexate Non-Proprietary Name: MethotrexateTabletOralMajor PharmaceuticalsACTIVE
16729-229Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousAccord Healthcare Inc.ACTIVE
16729-230Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousAccord Healthcare Inc.ACTIVE
16729-244Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousAccord Healthcare Inc.ACTIVE
16729-277Methotrexate Non-Proprietary Name: MethotrexateInjectionIntra-arterial; Intramuscular; Intrathecal; IntravenousAccord Healthcare, Inc.ACTIVE
16729-486Methotrexate Non-Proprietary Name: MethotrexateTabletOralAccord Healthcare Inc.ACTIVE
16729-522Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, SolutionIntravenousAccord Healthcare Inc.ACTIVE
42291-505Methotrexate Non-Proprietary Name: MethotrexateTabletOralAvkareACTIVE
42367-531Pemfexy Non-Proprietary Name: PemetrexedInjectionIntravenousEagle Pharmaceuticals, Inc.ACTIVE
43598-370Pemetrexed Disodium Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousDr. Reddys Laboratories IncACTIVE
43598-386Pemetrexed Disodium Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousDr. Reddys Laboratories IncACTIVE
43598-387Pemetrexed Disodium Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousDr. Reddys Laboratories IncACTIVE
47335-235Methotrexate Non-Proprietary Name: Methotrexate SodiumTabletOralSun Pharmaceutical Industries, Inc.ACTIVE
47781-482Methotrexate Non-Proprietary Name: MethotrexateTabletOralAlvogen Inc.ACTIVE
50090-3418Methotrexate Non-Proprietary Name: Methotrexate SodiumTabletOralA-s Medication SolutionsACTIVE
50090-5457Methotrexate Non-Proprietary Name: MethotrexateTabletOralA-s Medication SolutionsACTIVE
50268-527Methotrexate Non-Proprietary Name: MethotrexateTabletOralAvpakACTIVE
50742-340Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousIngenus Pharmaceuticals, LlcACTIVE
50742-341Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousIngenus Pharmaceuticals, LlcACTIVE
51079-670Methotrexate Non-Proprietary Name: MethotrexateTabletOralMylan Institutional Inc.ACTIVE
51285-366Trexall Non-Proprietary Name: MethotrexateTablet, Film CoatedOralTeva Women's Health, Inc.ACTIVE
51285-367Trexall Non-Proprietary Name: MethotrexateTablet, Film CoatedOralTeva Women's Health, Inc.ACTIVE
51285-368Trexall Non-Proprietary Name: MethotrexateTablet, Film CoatedOralTeva Women's Health, Inc.ACTIVE
51285-369Trexall Non-Proprietary Name: MethotrexateTablet, Film CoatedOralTeva Women's Health, Inc.ACTIVE
51407-121Methotrexate Non-Proprietary Name: MethotrexateTabletOralGolden State Medical Supply, Inc.ACTIVE
52652-2001Xatmep Non-Proprietary Name: MethotrexateSolutionOralAzurity Pharmaceuticals, Inc.ACTIVE
54436-010Otrexup Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-012Otrexup Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-015Otrexup Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-017Otrexup Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-020Otrexup Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-022Otrexup Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
54436-025Otrexup Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousAntares Pharma, Inc.ACTIVE
55150-381Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousAuromedics Pharma LlcACTIVE
55150-382Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousAuromedics Pharma LlcACTIVE
55150-383Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousAuromedics Pharma LlcACTIVE
59137-505Rasuvo Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-510Rasuvo Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-515Rasuvo Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-520Rasuvo Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-525Rasuvo Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-530Rasuvo Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-535Rasuvo Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-540Rasuvo Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59137-550Rasuvo Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousMedexus Pharma Inc.ACTIVE
59651-182Methotrexate Non-Proprietary Name: MethotrexateTabletOralAurobindo Pharma LimitedACTIVE
60505-6065Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousApotex CorpACTIVE
60505-6066Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousApotex CorpACTIVE
60505-6067Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousApotex CorpACTIVE
60505-6068Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousApotex CorpACTIVE
61703-350Methotrexate Non-Proprietary Name: MethotrexateInjection, SolutionIntramuscular; Intravenous; SubcutaneousHospira, Inc.ACTIVE
61703-408Methotrexate Non-Proprietary Name: MethotrexateInjection, SolutionIntramuscular; Intrathecal; Intravenous; SubcutaneousHospira, Inc.ACTIVE
63323-122Methotrexate Non-Proprietary Name: Methotrexate SodiumInjection, Powder, Lyophilized, For SolutionIntra-arterial; Intramuscular; Intrathecal; IntravenousFresenius Kabi Usa, LlcACTIVE
63323-123Methotrexate Non-Proprietary Name: Methotrexate SodiumInjection, SolutionIntra-arterial; Intramuscular; IntravenousFresenius Kabi Usa, LlcACTIVE
63323-134Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousFresenius Kabi Usa, LlcACTIVE
63323-450Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousFresenius Kabi Usa, LlcACTIVE
63323-621Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousFresenius Kabi Usa, LlcACTIVE
63323-622Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousFresenius Kabi Usa, LlcACTIVE
66220-807Reditrex Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousCumberland Pharmaceuticals Inc.ACTIVE
66220-810Reditrex Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousCumberland Pharmaceuticals Inc.ACTIVE
66220-812Reditrex Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousCumberland Pharmaceuticals Inc.ACTIVE
66220-815Reditrex Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousCumberland Pharmaceuticals Inc.ACTIVE
66220-817Reditrex Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousCumberland Pharmaceuticals Inc.ACTIVE
66220-820Reditrex Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousCumberland Pharmaceuticals Inc.ACTIVE
66220-822Reditrex Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousCumberland Pharmaceuticals Inc.ACTIVE
66220-825Reditrex Non-Proprietary Name: MethotrexateInjection, SolutionSubcutaneousCumberland Pharmaceuticals Inc.ACTIVE
67184-0503Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousQilu Pharmaceutical Co., Ltd.ACTIVE
67184-0504Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousQilu Pharmaceutical Co., Ltd.ACTIVE
68001-535Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousBluepoint LaboratoriesACTIVE
68001-536Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousBluepoint LaboratoriesACTIVE
68001-537Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousBluepoint LaboratoriesACTIVE
68001-538Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousBluepoint LaboratoriesACTIVE
68001-539Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousBluepoint LaboratoriesACTIVE
68001-543Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousBluepoint LaboratoriesACTIVE
68001-544Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousBluepoint LaboratoriesACTIVE
68001-547Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousBluepoint LaboratoriesACTIVE
68001-548Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousBluepoint LaboratoriesACTIVE
68001-549Pemetrexed Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousBluepoint LaboratoriesACTIVE
68001-550Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, SolutionIntravenousBluepoint LaboratoriesACTIVE
68001-551Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, SolutionIntravenousBluepoint LaboratoriesACTIVE
68001-552Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, SolutionIntravenousBluepoint LaboratoriesACTIVE
68001-553Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, SolutionIntravenousBluepoint LaboratoriesACTIVE
68382-775Methotrexate Non-Proprietary Name: MethotrexateTabletOralZydus Pharmaceuticals Usa Inc.ACTIVE
69238-1423Methotrexate Non-Proprietary Name: MethotrexateTabletOralAmneal Pharmaceuticals Ny LlcACTIVE
70121-1233Pemetrexed Disodium Non-Proprietary Name: PemetrexedInjection, Powder, Lyophilized, For SolutionIntravenousAmneal Pharmaceuticals LlcACTIVE
70518-1398Methotrexate Non-Proprietary Name: MethotrexateTabletOralRemedyrepack Inc.ACTIVE
70518-2711Methotrexate Sodium Non-Proprietary Name: Methotrexate SodiumTabletOralRemedyrepack Inc.ACTIVE
70518-3263Methotrexate Non-Proprietary Name: MethotrexateTabletOralRemedyrepack Inc.ACTIVE
70710-1654Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousZydus Pharmaceuticals Usa Inc.ACTIVE
70710-1655Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousZydus Pharmaceuticals Usa Inc.ACTIVE
70710-1674Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousZydus Pharmaceuticals Usa Inc.ACTIVE
70771-1058Methotrexate Non-Proprietary Name: MethotrexateTabletOralZydus Lifesciences LimitedACTIVE
70771-1691Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousZydus Lifesciences LimitedACTIVE
70771-1692Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousZydus Lifesciences LimitedACTIVE
70771-1693Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousZydus Lifesciences LimitedACTIVE
70860-202Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousAthenex Pharmaceutical Division, Llc.ACTIVE
70860-203Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousAthenex Pharmaceutical Division, Llc.ACTIVE
71288-166Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousMeitheal Pharmaceuticals Inc.ACTIVE
71288-167Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousMeitheal Pharmaceuticals Inc.ACTIVE
71335-0782Methotrexate Non-Proprietary Name: MethotrexateTabletOralBryant Ranch PrepackACTIVE
71335-1118Methotrexate Non-Proprietary Name: MethotrexateTabletOralBryant Ranch PrepackACTIVE
71335-1772Methotrexate Non-Proprietary Name: MethotrexateTabletOralBryant Ranch PrepackACTIVE
72338-100Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousWaverley Pharma IncACTIVE
72338-101Pemetrexed Non-Proprietary Name: Pemetrexed DisodiumInjection, Powder, Lyophilized, For SolutionIntravenousWaverley Pharma IncACTIVE