Tyrosine Kinase Inhibitors [MoA] - N0000020001

Pharmacologic Code	N0000020001
Pharmacologic Name	Tyrosine Kinase Inhibitors
Pharmacologic Uses	kinase inhibitor
Pharmacologic Concept	Mechanisms of Action - [MoA]
Pharmacologic Concept Description	This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

The table contains 17 products whose active ingredient are classified under the same pharmacologic class Tyrosine Kinase Inhibitors [MoA].

	NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
	0069-0334	Litfulo	Non-Proprietary Name: Ritlecitinib	Capsule	Oral	Pfizer Laboratories Div Pfizer Inc	ACTIVE
	0078-0694	Zykadia	Non-Proprietary Name: Ceritinib	Tablet, Film Coated	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	0310-0512	Calquence	Non-Proprietary Name: Acalabrutinib	Capsule, Gelatin Coated	Oral	Astrazeneca Pharmaceuticals Lp	ACTIVE
	0310-3512	Calquence	Non-Proprietary Name: Acalabrutinib	Tablet, Film Coated	Oral	Astrazeneca Pharmaceuticals Lp	ACTIVE
	45629-089	Fotivda	Non-Proprietary Name: Tivozanib	Capsule	Oral	Aveo Pharmaceuticals, Inc.	ACTIVE
	45629-134	Fotivda	Non-Proprietary Name: Tivozanib	Capsule	Oral	Aveo Pharmaceuticals, Inc.	ACTIVE
	51144-001	Tukysa	Non-Proprietary Name: Tucatinib	Tablet	Oral	Seagen Inc.	ACTIVE
	51144-002	Tukysa	Non-Proprietary Name: Tucatinib	Tablet	Oral	Seagen Inc.	ACTIVE
	63020-090	Alunbrig	Non-Proprietary Name: Brigatinib	Tablet, Film Coated	Oral	Takeda Pharmaceuticals America, Inc.	ACTIVE
	63020-113	Alunbrig	Non-Proprietary Name: Brigatinib	Tablet, Film Coated	Oral	Takeda Pharmaceuticals America, Inc.	ACTIVE
	63020-180	Alunbrig	Non-Proprietary Name: Brigatinib	Tablet, Film Coated	Oral	Takeda Pharmaceuticals America, Inc.	ACTIVE
	65597-407	Turalio	Non-Proprietary Name: Pexidartinib Hydrochloride	Capsule	Oral	Daiichi Sankyo, Inc.	ACTIVE
	72064-110	Ayvakit	Non-Proprietary Name: Avapritinib	Tablet, Film Coated	Oral	Blueprint Medicines Corporation	ACTIVE
	72064-120	Ayvakit	Non-Proprietary Name: Avapritinib	Tablet, Film Coated	Oral	Blueprint Medicines Corporation	ACTIVE
	72064-125	Ayvakit	Non-Proprietary Name: Avapritinib	Tablet, Film Coated	Oral	Blueprint Medicines Corporation	ACTIVE
	72064-130	Ayvakit	Non-Proprietary Name: Avapritinib	Tablet, Film Coated	Oral	Blueprint Medicines Corporation	ACTIVE
	72064-150	Ayvakit	Non-Proprietary Name: Avapritinib	Tablet, Film Coated	Oral	Blueprint Medicines Corporation	ACTIVE