HER1 Antagonists [MoA] - N0000020010

Pharmacologic Code	N0000020010
Pharmacologic Name	HER1 Antagonists
Pharmacologic Uses	epidermal growth factor receptor (EGFR) antagonist kinase inhibitor
Pharmacologic Concept	Mechanisms of Action - [MoA]
Pharmacologic Concept Description	This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

The table contains 6 products whose active ingredient are classified under the same pharmacologic class HER1 Antagonists [MoA].

	NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
	0002-7716	Portrazza	Non-Proprietary Name: Necitumumab	Solution	Intravenous	Eli Lilly And Company	ACTIVE
	55513-954	Vectibix	Non-Proprietary Name: Panitumumab	Solution	Intravenous	Amgen Inc	ACTIVE
	55513-956	Vectibix	Non-Proprietary Name: Panitumumab	Solution	Intravenous	Amgen Inc	ACTIVE
	63020-040	Exkivity	Non-Proprietary Name: Mobocertinib	Capsule	Oral	Takeda Pharmaceuticals America, Inc.	ACTIVE
	66733-948	Erbitux	Non-Proprietary Name: Cetuximab	Solution	Intravenous	Imclone Llc	ACTIVE
	66733-958	Erbitux	Non-Proprietary Name: Cetuximab	Solution	Intravenous	Imclone Llc	ACTIVE