CD20-directed Antibody Interactions [MoA] - N0000175078

Pharmacologic Code	N0000175078
Pharmacologic Name	CD20-directed Antibody Interactions
Pharmacologic Uses	CD20-directed cytolytic antibody
Pharmacologic Concept	Mechanisms of Action - [MoA]
Pharmacologic Concept Description	This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

The table contains 15 products whose active ingredient are classified under the same pharmacologic class CD20-directed Antibody Interactions [MoA].

	NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
	0069-0238	Ruxience	Non-Proprietary Name: Rituximab-pvvr	Injection, Solution	Intravenous	Pfizer Laboratories Div Pfizer Inc	ACTIVE
	0069-0249	Ruxience	Non-Proprietary Name: Rituximab-pvvr	Injection, Solution	Intravenous	Pfizer Laboratories Div Pfizer Inc	ACTIVE
	0078-0669	Arzerra	Non-Proprietary Name: Ofatumumab	Injection, Solution	Intravenous	Novartis Pharmaceuticals Corporation	ACTIVE
	0078-0690	Arzerra	Non-Proprietary Name: Ofatumumab	Injection, Solution	Intravenous	Novartis Pharmaceuticals Corporation	ACTIVE
	0078-1007	Kesimpta	Non-Proprietary Name: Ofatumumab	Injection, Solution	Subcutaneous	Novartis Pharmaceuticals Corporation	ACTIVE
	50242-051	Rituxan	Non-Proprietary Name: Rituximab	Injection, Solution	Intravenous	Genentech, Inc.	ACTIVE
	50242-053	Rituxan	Non-Proprietary Name: Rituximab	Injection, Solution	Intravenous	Genentech, Inc.	ACTIVE
	50242-070	Gazyva	Non-Proprietary Name: Obinutuzumab	Injection, Solution, Concentrate	Intravenous	Genentech, Inc.	ACTIVE
	50242-108	Rituxan Hycela	Non-Proprietary Name: Rituximab And Hyaluronidase	Injection, Solution	Subcutaneous	Genentech, Inc.	ACTIVE
	50242-109	Rituxan Hycela	Non-Proprietary Name: Rituximab And Hyaluronidase	Injection, Solution	Subcutaneous	Genentech, Inc.	ACTIVE
	50242-150	Ocrevus	Non-Proprietary Name: Ocrelizumab	Injection	Intravenous	Genentech, Inc.	ACTIVE
	55513-224	Riabni	Non-Proprietary Name: Rituximab-arrx	Injection, Solution	Intravenous	Amgen Inc	ACTIVE
	55513-326	Riabni	Non-Proprietary Name: Rituximab-arrx	Injection, Solution	Intravenous	Amgen Inc	ACTIVE
	63459-103	Truxima	Non-Proprietary Name: Rituximab-abbs	Injection, Solution	Intravenous	Cephalon, Inc.	ACTIVE
	63459-104	Truxima	Non-Proprietary Name: Rituximab-abbs	Injection, Solution	Intravenous	Cephalon, Inc.	ACTIVE