Endothelin Receptor Antagonists [MoA] - N0000175364

Name: Table of NDC products with endothelin receptor antagonists
Creator: U.S. Food & Drug Administration
License: https://creativecommons.org/licenses/by-nc-sa/4.0/

Pharmacologic Class Information

Pharmacologic Code	N0000175364
Pharmacologic Name	Endothelin Receptor Antagonists
Pharmacologic Uses	endothelin and angiotensin II receptor antagonist endothelin receptor antagonist
Pharmacologic Concept	Mechanisms of Action - [MoA]
Pharmacologic Concept Description	This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

NDC Products with Endothelin Receptor Antagonists

The table contains 37 products whose active ingredient are classified under the same pharmacologic class Endothelin Receptor Antagonists [MoA].

NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
0378-4270	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Mylan Pharmaceuticals Inc.	ACTIVE
0378-4271	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Mylan Pharmaceuticals Inc.	ACTIVE
0591-2405		Non-Proprietary Name: Ambrisentan	Tablet, Film Coated		Actavis Pharma, Inc.	ACTIVE
0591-2405	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Actavis Pharma, Inc.	ACTIVE
0591-2406		Non-Proprietary Name: Ambrisentan	Tablet, Film Coated		Actavis Pharma, Inc.	ACTIVE
0591-2406	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Actavis Pharma, Inc.	ACTIVE
0591-2511		Non-Proprietary Name: Bosentan	Tablet, Film Coated		Actavis Pharma, Inc.	ACTIVE
0591-2511	Bosentan	Non-Proprietary Name: Bosentan	Tablet, Film Coated	Oral	Actavis Pharma, Inc.	ACTIVE
0591-2512		Non-Proprietary Name: Bosentan	Tablet, Film Coated		Actavis Pharma, Inc.	ACTIVE
0591-2512	Bosentan	Non-Proprietary Name: Bosentan	Tablet, Film Coated	Oral	Actavis Pharma, Inc.	ACTIVE
42794-051	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Sigmapharm Laboratories, Llc	ACTIVE
42794-052	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Sigmapharm Laboratories, Llc	ACTIVE
47335-038	Bosentan	Non-Proprietary Name: Bosentan	Tablet, Film Coated	Oral	Sun Pharmaceutical Industries, Inc.	ACTIVE
47335-039	Bosentan	Non-Proprietary Name: Bosentan	Tablet, Film Coated	Oral	Sun Pharmaceutical Industries, Inc.	ACTIVE
47335-236	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Sun Pharmaceutical Industries, Inc.	ACTIVE
47335-237	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Sun Pharmaceutical Industries, Inc.	ACTIVE
59651-494	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Aurobindo Pharma Limited	ACTIVE
59651-495	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Aurobindo Pharma Limited	ACTIVE
60505-4552	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Apotex Corp.	ACTIVE
60505-4553	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Apotex Corp.	ACTIVE
61958-0801	Letairis	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Gilead Sciences, Inc	ACTIVE
61958-0802	Letairis	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Gilead Sciences, Inc	ACTIVE
65162-873	Bosentan	Non-Proprietary Name: Bosentan	Tablet, Film Coated	Oral	Amneal Pharmaceuticals Llc	ACTIVE
65162-874	Bosentan	Non-Proprietary Name: Bosentan	Tablet, Film Coated	Oral	Amneal Pharmaceuticals Llc	ACTIVE
66215-101	Tracleer	Non-Proprietary Name: Bosentan	Tablet, Film Coated	Oral	Actelion Pharmaceuticals Us, Inc.	ACTIVE
66215-102	Tracleer	Non-Proprietary Name: Bosentan	Tablet, Film Coated	Oral	Actelion Pharmaceuticals Us, Inc.	ACTIVE
66215-103	Tracleer	Non-Proprietary Name: Bosentan	Tablet, For Suspension	Oral	Actelion Pharmaceuticals Us, Inc.	ACTIVE
66215-232	Tracleer	Non-Proprietary Name: Bosentan	Tablet, For Suspension	Oral	Actelion Pharmaceuticals Us, Inc.	ACTIVE
66215-501	Opsumit	Non-Proprietary Name: Macitentan	Tablet, Film Coated	Oral	Actelion Pharmaceuticals Us, Inc.	ACTIVE
66215-812	Opsynvi	Non-Proprietary Name: Macitentan And Tadalafil	Tablet, Film Coated	Oral	Actelion Pharmaceuticals Us, Inc.	ACTIVE
66215-814	Opsynvi	Non-Proprietary Name: Macitentan And Tadalafil	Tablet, Film Coated	Oral	Actelion Pharmaceuticals Us, Inc.	ACTIVE
68382-446	Bosentan	Non-Proprietary Name: Bosentan	Tablet, Coated	Oral	Zydus Pharmaceuticals Usa Inc.	ACTIVE
68382-447	Bosentan	Non-Proprietary Name: Bosentan	Tablet, Coated	Oral	Zydus Pharmaceuticals Usa Inc.	ACTIVE
69097-386	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Cipla Usa Inc.	ACTIVE
69097-387	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Cipla Usa Inc.	ACTIVE
70710-1179	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Zydus Pharmaceuticals Usa Inc.	ACTIVE
70710-1180	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Zydus Pharmaceuticals Usa Inc.	ACTIVE
70771-1017	Bosentan	Non-Proprietary Name: Bosentan	Tablet	Oral	Zydus Lifesciences Limited	ACTIVE
70771-1018	Bosentan	Non-Proprietary Name: Bosentan	Tablet	Oral	Zydus Lifesciences Limited	ACTIVE
70771-1363	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Zydus Lifesciences Limited	ACTIVE
70771-1364	Ambrisentan	Non-Proprietary Name: Ambrisentan	Tablet, Film Coated	Oral	Zydus Lifesciences Limited	ACTIVE