Complement Inhibitors [MoA] - N0000175974

Pharmacologic Code	N0000175974
Pharmacologic Name	Complement Inhibitors
Pharmacologic Uses	complement inhibitor
Pharmacologic Concept	Mechanisms of Action - [MoA]
Pharmacologic Concept Description	This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

The table contains 11 products whose active ingredient are classified under the same pharmacologic class Complement Inhibitors [MoA].

	NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
	25682-001	Soliris	Non-Proprietary Name: Eculizumab	Injection, Solution, Concentrate	Intravenous	Alexion Pharmaceuticals Inc.	ACTIVE
	25682-022	Ultomiris	Non-Proprietary Name: Ravulizumab	Solution, Concentrate	Intravenous	Alexion Pharmaceuticals Inc.	ACTIVE
	25682-025	Ultomiris	Non-Proprietary Name: Ravulizumab	Solution, Concentrate	Intravenous	Alexion Pharmaceuticals Inc.	ACTIVE
	25682-028	Ultomiris	Non-Proprietary Name: Ravulizumab	Solution, Concentrate	Intravenous	Alexion Pharmaceuticals Inc.	ACTIVE
	50474-990	Zilbrysq	Non-Proprietary Name: Zilucoplan	Injection, Solution	Subcutaneous	Ucb, Inc.	ACTIVE
	50474-991	Zilbrysq	Non-Proprietary Name: Zilucoplan	Injection, Solution	Subcutaneous	Ucb, Inc.	ACTIVE
	50474-992	Zilbrysq	Non-Proprietary Name: Zilucoplan	Injection, Solution	Subcutaneous	Ucb, Inc.	ACTIVE
	61755-014	Veopoz	Non-Proprietary Name: Pozelimab	Injection, Solution	Intravenous; Subcutaneous	Regeneron Pharmaceuticals, Inc.	ACTIVE
	73606-010	Empaveli	Non-Proprietary Name: Pegcetacoplan	Injection, Solution	Subcutaneous	Apellis Pharmaceuticals, Inc.	ACTIVE
	73606-020	Syfovre	Non-Proprietary Name: Pegcetacoplan	Injection, Solution	Intravitreal	Apellis Pharmaceuticals, Inc.	ACTIVE
	82829-002	Izervay	Non-Proprietary Name: Avacincaptad Pegol	Injection	Intravitreal	Astellas Pharma Us, Inc.	ACTIVE