Smoothened Receptor Antagonists [MoA] - N0000184148

Pharmacologic Code	N0000184148
Pharmacologic Name	Smoothened Receptor Antagonists
Pharmacologic Uses	hedgehog pathway inhibitor
Pharmacologic Concept	Mechanisms of Action - [MoA]
Pharmacologic Concept Description	This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

The table contains 4 products whose active ingredient are classified under the same pharmacologic class Smoothened Receptor Antagonists [MoA].

	NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
	0069-0298	Daurismo	Non-Proprietary Name: Glasdegib	Tablet, Film Coated	Oral	Pfizer Laboratories Div Pfizer Inc	ACTIVE
	0069-1531	Daurismo	Non-Proprietary Name: Glasdegib	Tablet, Film Coated	Oral	Pfizer Laboratories Div Pfizer Inc	ACTIVE
	47335-303	Odomzo	Non-Proprietary Name: Sonidegib	Capsule	Oral	Sun Pharmaceutical Industries, Inc.	ACTIVE
	50242-140	Erivedge	Non-Proprietary Name: Vismodegib	Capsule	Oral	Genentech, Inc.	ACTIVE