Kallikrein Inhibitors [MoA] - N0000184151

Pharmacologic Code	N0000184151
Pharmacologic Name	Kallikrein Inhibitors
Pharmacologic Uses	human C1 esterase inhibitor plasma kallikrein inhibitor
Pharmacologic Concept	Mechanisms of Action - [MoA]
Pharmacologic Concept Description	This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

The table contains 12 products whose active ingredient are classified under the same pharmacologic class Kallikrein Inhibitors [MoA].

	NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
	42227-081	Cinryze	Non-Proprietary Name: Human C1-esterase Inhibitor	Injection, Powder, Lyophilized, For Solution	Intravenous	Takeda Pharmaceuticals America, Inc.	ACTIVE
	82928-300	Ekterly	Non-Proprietary Name: Sebetralstat	Tablet	Oral	Kalvista Pharmaceuticals Ltd	ACTIVE
	72769-101	Orladeyo	Non-Proprietary Name: Berotralstat Hydrochloride	Capsule	Oral	Biocryst Pharmaceuticals, Inc.	ACTIVE
	47783-644	Takhzyro	Non-Proprietary Name: Lanadelumab-flyo	Injection, Solution	Subcutaneous	Takeda Pharmaceuticals America, Inc.	ACTIVE
	47783-646	Takhzyro	Non-Proprietary Name: Lanadelumab-flyo	Solution	Subcutaneous	Takeda Pharmaceuticals America, Inc.	ACTIVE
	72769-111	Orladeyo	Non-Proprietary Name: Berotralstat Hydrochloride	Pellet	Oral	Biocryst Pharmaceuticals, Inc.	ACTIVE
	72769-112	Orladeyo	Non-Proprietary Name: Berotralstat Hydrochloride	Pellet	Oral	Biocryst Pharmaceuticals, Inc.	ACTIVE
	72769-113	Orladeyo	Non-Proprietary Name: Berotralstat Hydrochloride	Pellet	Oral	Biocryst Pharmaceuticals, Inc.	ACTIVE
	47783-101	Kalbitor	Non-Proprietary Name: Ecallantide	Injection, Solution	Subcutaneous	Takeda Pharmaceuticals America, Inc.	ACTIVE
	72769-102	Orladeyo	Non-Proprietary Name: Berotralstat Hydrochloride	Capsule	Oral	Biocryst Pharmaceuticals, Inc.	ACTIVE
	47783-645	Takhzyro	Non-Proprietary Name: Lanadelumab-flyo	Solution	Subcutaneous	Takeda Pharmaceuticals America, Inc.	ACTIVE
	72769-114	Orladeyo	Non-Proprietary Name: Berotralstat Hydrochloride	Pellet	Oral	Biocryst Pharmaceuticals, Inc.	ACTIVE