Guanylate Cyclase Activators [MoA] - N0000185499

Pharmacologic Code	N0000185499
Pharmacologic Name	Guanylate Cyclase Activators
Pharmacologic Uses	guanylate cyclase-C agonist
Pharmacologic Concept	Mechanisms of Action - [MoA]
Pharmacologic Concept Description	This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

The table contains 4 products whose active ingredient are classified under the same pharmacologic class Guanylate Cyclase Activators [MoA].

	NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
	0456-1201	Linzess	Non-Proprietary Name: Linaclotide	Capsule, Gelatin Coated	Oral	Allergan, Inc.	ACTIVE
	0456-1202	Linzess	Non-Proprietary Name: Linaclotide	Capsule, Gelatin Coated	Oral	Allergan, Inc.	ACTIVE
	0456-1203	Linzess	Non-Proprietary Name: Linaclotide	Capsule, Gelatin Coated	Oral	Allergan, Inc.	ACTIVE
	65649-003	Trulance Immediate release	Non-Proprietary Name: Plecanatide	Tablet	Oral	Salix Pharmaceuticals Inc.	ACTIVE