Guanylate Cyclase-C Agonist [EPC] - N0000185500

Pharmacologic Code	N0000185500
Pharmacologic Name	Guanylate Cyclase-C Agonist
Pharmacologic Uses	guanylate cyclase-C agonist
Pharmacologic Concept	Established Pharmacologic Classes - [EPC]
Pharmacologic Concept Description	An established pharmacologic class is a term or phrase that is scientifically valid and clinically meaningful according to the following definitions: A scientifically valid pharmacologic class is supported by documented and submitted empiric evidence showing that the drug's pharmacologic class is known, not theoretical, and relevant and specific to the indication. A clinically meaningful pharmacologic class term or phrase enhances the ability of professionals to understand physiologic effects related to the indication or to anticipate undesirable effects that may be associated with the drug or pharmacologic class.

The table contains 4 products whose active ingredient are classified under the same pharmacologic class Guanylate Cyclase-C Agonist [EPC].

	NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
	0456-1201	Linzess	Non-Proprietary Name: Linaclotide	Capsule, Gelatin Coated	Oral	Allergan, Inc.	ACTIVE
	0456-1202	Linzess	Non-Proprietary Name: Linaclotide	Capsule, Gelatin Coated	Oral	Allergan, Inc.	ACTIVE
	0456-1203	Linzess	Non-Proprietary Name: Linaclotide	Capsule, Gelatin Coated	Oral	Allergan, Inc.	ACTIVE
	65649-003	Trulance Immediate release	Non-Proprietary Name: Plecanatide	Tablet	Oral	Salix Pharmaceuticals Inc.	ACTIVE