Cytochrome P450 2C8 Inducers [MoA] - N0000187063

Pharmacologic Code	N0000187063
Pharmacologic Name	Cytochrome P450 2C8 Inducers
Pharmacologic Uses	antiepileptic drug (AED) kinase inhibitor pyruvate kinase activator
Pharmacologic Concept	Mechanisms of Action - [MoA]
Pharmacologic Concept Description	This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

The table contains 105 products whose active ingredient are classified under the same pharmacologic class Cytochrome P450 2C8 Inducers [MoA].

	NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
	0069-5471	Cerebyx	Non-Proprietary Name: Fosphenytoin Sodium	Injection, Solution	Intramuscular; Intravenous	Pfizer Laboratories Div Pfizer Inc	ACTIVE
	0069-5474	Cerebyx	Non-Proprietary Name: Fosphenytoin Sodium	Injection, Solution	Intramuscular; Intravenous	Pfizer Laboratories Div Pfizer Inc	ACTIVE
	0069-6001	Cerebyx	Non-Proprietary Name: Fosphenytoin Sodium	Injection, Solution	Intramuscular; Intravenous	Pfizer Laboratories Div Pfizer Inc	ACTIVE
	0071-0007	Dilantin Infatabs	Non-Proprietary Name: Phenytoin	Tablet, Chewable	Oral	Parke-davis Div Of Pfizer Inc	ACTIVE
	0071-0369	Dilantin	Non-Proprietary Name:			Parke-davis Div Of Pfizer Inc
	0071-0369	Dilantin	Non-Proprietary Name: Extended Phenytoin Sodium	Capsule	Oral	Parke-davis Div Of Pfizer Inc	ACTIVE
	0071-3740	Dilantin	Non-Proprietary Name: Extended Phenytoin Sodium	Capsule	Oral	Parke-davis Div Of Pfizer Inc	ACTIVE
	0078-0526	Tasigna	Non-Proprietary Name: Nilotinib	Capsule	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	0078-0592	Tasigna	Non-Proprietary Name: Nilotinib	Capsule	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	0078-0681	Tafinlar	Non-Proprietary Name: Dabrafenib	Capsule	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	0078-0682	Tafinlar	Non-Proprietary Name: Dabrafenib	Capsule	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	0078-0951	Tasigna	Non-Proprietary Name: Nilotinib	Capsule	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	0078-1154	Tafinlar	Non-Proprietary Name: Dabrafenib	Tablet, For Suspension	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	0121-0892	Phenytoin	Non-Proprietary Name: Phenytoin	Suspension	Oral	Pai Holdings, Llc Dba Pai Pharma	ACTIVE
	0143-9782	Fosphenytoin Sodium	Non-Proprietary Name: Fosphenytoin Sodium	Injection, Solution	Intramuscular; Intravenous	West-ward Pharmaceuticals Corp	ACTIVE
	0143-9788	Fosphenytoin Sodium	Non-Proprietary Name: Fosphenytoin Sodium	Injection, Solution	Intramuscular; Intravenous	West-ward Pharmaceuticals Corp	ACTIVE
	0378-2670	Phenytek	Non-Proprietary Name: Extended Phenytoin Sodium	Capsule, Extended Release	Oral	Mylan Pharmaceuticals Inc.	ACTIVE
	0378-3750	Phenytek	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	Mylan Pharmaceuticals Inc.	ACTIVE
	0404-9808	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Injection	Intramuscular; Intravenous	Henry Schein, Inc.	ACTIVE
	0404-9932	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Injection	Intramuscular; Intravenous	Henry Schein, Inc.	ACTIVE
	0615-8020	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	Ncs Healthcare Of Ky, Llc Dba Vangard Labs	ACTIVE
	0615-8424	Phenytoin Infatabs	Non-Proprietary Name: Phenytoin	Tablet, Chewable	Oral	Ncs Healthcare Of Ky, Llc Dba Vangard Labs	ACTIVE
	0615-8556	Extended Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule	Oral	Ncs Healthcare Of Ky, Llc Dba Vangard Labs	ACTIVE
	0641-0493	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Injection	Intramuscular; Intravenous	Hikma Pharmaceuticals Usa Inc.	ACTIVE
	0641-2555	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Injection	Intramuscular; Intravenous	Hikma Pharmaceuticals Usa Inc.	ACTIVE
	0641-6136	Fosphenytoin Sodium	Non-Proprietary Name: Fosphenytoin Sodium	Injection	Intramuscular; Intravenous	Hikma Pharmaceuticals Usa Inc.	ACTIVE
	0641-6137	Fosphenytoin Sodium	Non-Proprietary Name: Fosphenytoin Sodium	Injection	Intramuscular; Intravenous	Hikma Pharmaceuticals Usa Inc.	ACTIVE
	0641-6138	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Injection	Intramuscular; Intravenous	Hikma Pharmaceuticals Usa Inc.	ACTIVE
	0641-6139	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Injection	Intramuscular; Intravenous	Hikma Pharmaceuticals Usa Inc.	ACTIVE
	0904-7199	Phenytoin	Non-Proprietary Name: Phenytoin	Tablet, Chewable	Oral	Major Pharmaceuticals	ACTIVE
	17856-4070	Phenytoin	Non-Proprietary Name: Phenytoin	Suspension	Oral	Atlantic Biologicals Corp.	ACTIVE
	24338-154	Danziten	Non-Proprietary Name: Nilotinib	Tablet	Oral	Azurity Pharmaceuticals, Inc.	ACTIVE
	24338-155	Danziten	Non-Proprietary Name: Nilotinib	Tablet	Oral	Azurity Pharmaceuticals, Inc.	ACTIVE
	25021-798	Fosphenytoin Sodium	Non-Proprietary Name: Fosphenytoin Sodium	Injection, Solution	Intramuscular; Intravenous	Sagent Pharmaceuticals	ACTIVE
	29300-379	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	Unichem Pharmaceuticals (usa), Inc.	ACTIVE
	42192-614	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Injection	Intramuscular; Intravenous	Acella Pharmaceuticals, Llc	ACTIVE
	43063-492	Extended Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule	Oral	Pd-rx Pharmaceuticals, Inc.	ACTIVE
	50090-3539	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	A-s Medication Solutions	ACTIVE
	50090-5700	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	A-s Medication Solutions	ACTIVE
	51167-122	Orkambi	Non-Proprietary Name: Lumacaftor And Ivacaftor	Granule	Oral	Vertex Pharmaceuticals Incorporated	ACTIVE
	51167-500	Orkambi	Non-Proprietary Name: Lumacaftor And Ivacaftor	Granule	Oral	Vertex Pharmaceuticals Incorporated	ACTIVE
	51167-700	Orkambi	Non-Proprietary Name: Lumacaftor And Ivacaftor	Tablet, Film Coated	Oral	Vertex Pharmaceuticals Incorporated	ACTIVE
	51167-809	Orkambi	Non-Proprietary Name: Lumacaftor And Ivacaftor	Tablet, Film Coated	Oral	Vertex Pharmaceuticals Incorporated	ACTIVE
	51167-900	Orkambi	Non-Proprietary Name: Lumacaftor And Ivacaftor	Granule	Oral	Vertex Pharmaceuticals Incorporated	ACTIVE
	51407-982	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	Golden State Medical Supply, Inc.	ACTIVE
	51662-1250	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Injection	Intramuscular; Intravenous	Hf Acquisition Co Llc, Dba Healthfirst	ACTIVE
	51662-1251	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Injection	Intramuscular; Intravenous	Hf Acquisition Co Llc, Dba Healthfirst	ACTIVE
	51672-4069	Phenytoin	Non-Proprietary Name: Phenytoin	Suspension	Oral	Taro Pharmaceuticals U.s.a., Inc.	ACTIVE
	51672-4111	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	Taro Pharmaceuticals U.s.a., Inc.	ACTIVE
	51672-4146	Phenytoin	Non-Proprietary Name: Phenytoin	Tablet, Chewable	Oral	Taro Pharmaceuticals U.s.a., Inc	ACTIVE
	57664-808	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	Sun Pharmaceutical Industries, Inc.	ACTIVE
	58151-110	Dilantin	Non-Proprietary Name: Extended Phenytoin Sodium	Capsule, Extended Release	Oral	Viatris Specialty Llc	ACTIVE
	58151-115	Dilantin-125	Non-Proprietary Name: Phenytoin	Suspension	Oral	Viatris Specialty Llc	ACTIVE
	58151-118	Dilantin	Non-Proprietary Name: Extended Phenytoin Sodium	Capsule, Extended Release	Oral	Viatris Specialty Llc	ACTIVE
	59762-0531	Phenytoin	Non-Proprietary Name: Phenytoin	Suspension	Oral	Mylan Pharmaceuticals Inc.	ACTIVE
	60505-3801	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Apotex Corp.	ACTIVE
	60505-3802	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Apotex Corp.	ACTIVE
	60505-3803	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Apotex Corp.	ACTIVE
	60687-156	Phenytoin	Non-Proprietary Name: Phenytoin	Tablet, Chewable	Oral	American Health Packaging	ACTIVE
	60687-275	Phenytoin	Non-Proprietary Name: Phenytoin	Suspension	Oral	American Health Packaging	ACTIVE
	60687-841	Extended Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule	Oral	American Health Packaging	ACTIVE
	62756-299	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	Sun Pharmaceutical Industries, Inc.	ACTIVE
	62756-432	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	Sun Pharmaceutical Industries, Inc.	ACTIVE
	63323-403	Fosphenytoin	Non-Proprietary Name:			Fresenius Kabi Usa, Llc
	63323-403	Fosphenytoin	Non-Proprietary Name: Fosphenytoin Sodium	Injection, Solution	Intramuscular; Intravenous	Fresenius Kabi Usa, Llc	ACTIVE
	63629-2369	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	Bryant Ranch Prepack	ACTIVE
	64406-250	Skyclarys	Non-Proprietary Name: Omaveloxolone	Capsule	Oral	Biogen	ACTIVE
	64980-573	Phenytoin	Non-Proprietary Name: Phenytoin	Tablet, Chewable	Oral	Rising Pharma Holdings, Inc.	ACTIVE
	65162-212	Extended Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule	Oral	Amneal Pharmaceuticals Llc	ACTIVE
	65162-998	Fosphenytoin Sodium	Non-Proprietary Name: Fosphenytoin Sodium	Injection	Intramuscular; Intravenous	Amneal Pharmaceuticals Llc	ACTIVE
	65162-999	Fosphenytoin Sodium	Non-Proprietary Name: Fosphenytoin Sodium	Injection	Intramuscular; Intravenous	Amneal Pharmaceuticals Llc	ACTIVE
	65862-692		Non-Proprietary Name: Phenytoin Sodium	Capsule		Aurobindo Pharma Limited	ACTIVE
	65862-692	Extended Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule	Oral	Aurobindo Pharma Limited	ACTIVE
	66689-775	Phenytoin	Non-Proprietary Name: Phenytoin	Suspension	Oral	Vistapharm, Llc	ACTIVE
	66993-372	Phenytoin Infatabs	Non-Proprietary Name: Phenytoin	Tablet, Chewable	Oral	Prasco Laboratories	ACTIVE
	67046-1486	Phenytek	Non-Proprietary Name: Extended Phenytoin Sodium	Capsule, Extended Release	Oral	Coupler Llc	ACTIVE
	68083-460	Fosphenytoin Sodium	Non-Proprietary Name: Fosphenytoin Sodium	Injection, Solution	Intramuscular; Intravenous	Gland Pharma Limited	ACTIVE
	68083-461	Fosphenytoin Sodium	Non-Proprietary Name: Fosphenytoin Sodium	Injection, Solution	Intramuscular; Intravenous	Gland Pharma Limited	ACTIVE
	68462-621	Fosphenytoin Sodium	Non-Proprietary Name: Fosphenytoin Sodium	Injection, Solution	Intramuscular; Intravenous	Glenmark Pharmaceuticals Inc., Usa	ACTIVE
	68462-622	Fosphenytoin Sodium	Non-Proprietary Name: Fosphenytoin Sodium	Injection, Solution	Intramuscular; Intravenous	Glenmark Pharmaceuticals Inc., Usa	ACTIVE
	69097-030	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Cipla Usa Inc.	ACTIVE
	69097-031	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Cipla Usa Inc.	ACTIVE
	69097-032	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Cipla Usa Inc.	ACTIVE
	70121-1381	Fosphenytoin Sodium	Non-Proprietary Name: Fosphenytoin	Injection	Intramuscular; Intravenous	Amneal Pharmaceuticals Llc	ACTIVE
	70121-1390	Fosphenytoin Sodium	Non-Proprietary Name: Fosphenytoin	Injection	Intramuscular; Intravenous	Amneal Pharmaceuticals Llc	ACTIVE
	70518-0107	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	Remedyrepack Inc.	ACTIVE
	70518-0841	Phenytoin	Non-Proprietary Name: Phenytoin	Tablet, Chewable	Oral	Remedyrepack Inc.	ACTIVE
	70518-1776	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	Remedyrepack Inc.	ACTIVE
	70518-2227	Extended Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule	Oral	Remedyrepack Inc.	ACTIVE
	70518-2293	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	Remedyrepack Inc.	ACTIVE
	70518-4149	Phenytoin Infatabs	Non-Proprietary Name: Phenytoin	Tablet, Chewable	Oral	Remedyrepack Inc.	ACTIVE
	70518-4185	Dilantin	Non-Proprietary Name: Extended Phenytoin Sodium	Capsule	Oral	Remedyrepack Inc.	ACTIVE
	70518-4325	Dilantin	Non-Proprietary Name: Extended Phenytoin Sodium	Capsule, Extended Release	Oral	Remedyrepack Inc.	ACTIVE
	71334-205	Pyrukynd	Non-Proprietary Name: Mitapivat	Tablet, Film Coated	Oral	Agios Pharmaceuticals, Inc.	ACTIVE
	71334-210	Pyrukynd	Non-Proprietary Name: Mitapivat	Tablet, Film Coated	Oral	Agios Pharmaceuticals, Inc.	ACTIVE
	71334-215	Pyrukynd	Non-Proprietary Name: Mitapivat	Tablet, Film Coated	Oral	Agios Pharmaceuticals, Inc.	ACTIVE
	71334-220	Pyrukynd	Non-Proprietary Name: Mitapivat	Tablet, Film Coated	Oral	Agios Pharmaceuticals, Inc.	ACTIVE
	71610-479	Extended Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule	Oral	Aphena Pharma Solutions - Tennessee, Llc	ACTIVE
	71610-869	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	Aphena Pharma Solutions - Tennessee, Llc	ACTIVE
	71699-025	Xcopri	Non-Proprietary Name: Cenobamate	Tablet, Film Coated	Oral	Sk Life Science, Inc.	ACTIVE
	71699-050	Xcopri	Non-Proprietary Name: Cenobamate	Tablet, Film Coated	Oral	Sk Life Science, Inc.	ACTIVE
	71699-100	Xcopri	Non-Proprietary Name: Cenobamate	Tablet, Film Coated	Oral	Sk Life Science, Inc.	ACTIVE
	71699-150	Xcopri	Non-Proprietary Name: Cenobamate	Tablet, Film Coated	Oral	Sk Life Science, Inc.	ACTIVE
	71699-200	Xcopri	Non-Proprietary Name: Cenobamate	Tablet, Film Coated	Oral	Sk Life Science, Inc.	ACTIVE
	71872-7079	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Injection	Intramuscular; Intravenous	Medical Purchasing Solutions, Llc	ACTIVE
	72162-1646	Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule, Extended Release	Oral	Bryant Ranch Prepack	ACTIVE
	72162-2514	Extended Phenytoin Sodium	Non-Proprietary Name: Phenytoin Sodium	Capsule	Oral	Bryant Ranch Prepack	ACTIVE
	73179-250	Skyclarys	Non-Proprietary Name: Omaveloxolone	Capsule	Oral	Reata Pharmaceuticals, Inc.	ACTIVE