Organic Anion Transporting Polypeptide 1B3 Inhibitors [MoA] - N0000190108

Pharmacologic Code	N0000190108
Pharmacologic Name	Organic Anion Transporting Polypeptide 1B3 Inhibitors
Pharmacologic Uses	calcineurin-inhibitor immunosuppressant CMV DNA terminase complex inhibitor CYP3A inhibitor farnesyltransferase inhibitor hepatitis C virus (HCV) NS3/4A protease inhibitor hepatitis C virus (HCV) NS5A inhibitor histone deacetylase (HDAC) inhibitor kinase inhibitor nitroimidazole antimicrobial
Pharmacologic Concept	Mechanisms of Action - [MoA]
Pharmacologic Concept Description	This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

The table contains 28 products whose active ingredient are classified under the same pharmacologic class Organic Anion Transporting Polypeptide 1B3 Inhibitors [MoA].

	NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
	0003-3641	Evotaz	Non-Proprietary Name: Atazanavir And Cobicistat	Tablet	Oral	E.r. Squibb & Sons, L.l.c.	ACTIVE
	0006-3075	Prevymis	Non-Proprietary Name: Letermovir	Tablet, Film Coated	Oral	Merck Sharp & Dohme Llc	ACTIVE
	0006-3076	Prevymis	Non-Proprietary Name: Letermovir	Tablet, Film Coated	Oral	Merck Sharp & Dohme Llc	ACTIVE
	0006-5003	Prevymis	Non-Proprietary Name: Letermovir	Injection, Solution	Intravenous	Merck Sharp & Dohme Llc	ACTIVE
	0006-5004	Prevymis	Non-Proprietary Name: Letermovir	Injection, Solution	Intravenous	Merck Sharp & Dohme Llc	ACTIVE
	0024-4512	Fexinidazole	Non-Proprietary Name: Fexinidazole	Tablet	Oral	Sanofi-aventis U.s. Llc	ACTIVE
	0074-2600	Mavyret	Non-Proprietary Name: Glecaprevir And Pibrentasvir	Pellet	Oral	Abbvie Inc.	ACTIVE
	0074-2625	Mavyret	Non-Proprietary Name: Glecaprevir And Pibrentasvir	Tablet, Film Coated	Oral	Abbvie Inc.	ACTIVE
	0078-0681	Tafinlar	Non-Proprietary Name: Dabrafenib	Capsule	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	0078-0682	Tafinlar	Non-Proprietary Name: Dabrafenib	Capsule	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	0078-1154	Tafinlar	Non-Proprietary Name: Dabrafenib	Tablet, For Suspension	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	0703-4004	Romidepsin	Non-Proprietary Name: Romidepsin	Injection, Solution, Concentrate	Intravenous	Teva Parenteral Medicines, Inc.	ACTIVE
	50090-1723	Prezcobix	Non-Proprietary Name: Darunavir Ethanolate And Cobicistat	Tablet, Film Coated	Oral	A-s Medication Solutions	ACTIVE
	59676-575	Prezcobix	Non-Proprietary Name: Darunavir Ethanolate And Cobicistat	Tablet, Film Coated	Oral	Janssen Products Lp	ACTIVE
	59676-800	Symtuza	Non-Proprietary Name: Darunavir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	Tablet, Film Coated	Oral	Janssen Products Lp	ACTIVE
	61958-1201	Stribild	Non-Proprietary Name: Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Disoproxil Fumarate	Tablet, Film Coated	Oral	Gilead Sciences, Inc.	ACTIVE
	61958-1401	Tybost	Non-Proprietary Name: Cobicistat	Tablet, Film Coated	Oral	Gilead Sciences, Inc.	ACTIVE
	61958-1901	Genvoya	Non-Proprietary Name: Elvitegravir, Cobicistat, Emtricitabine, And Tenofovir Alafenamide	Tablet	Oral	Gilead Sciences, Inc.	ACTIVE
	61958-2201	Epclusa	Non-Proprietary Name: Velpatasvir And Sofosbuvir	Tablet, Film Coated	Oral	Gilead Sciences, Inc.	ACTIVE
	61958-2203	Epclusa	Non-Proprietary Name: Velpatasvir And Sofosbuvir	Tablet, Film Coated	Oral	Gilead Sciences, Inc.	ACTIVE
	61958-2204	Epclusa	Non-Proprietary Name: Velpatasvir And Sofosbuvir	Pellet	Oral	Gilead Sciences, Inc.	ACTIVE
	61958-2205	Epclusa	Non-Proprietary Name: Velpatasvir And Sofosbuvir	Pellet	Oral	Gilead Sciences, Inc.	ACTIVE
	61958-2401	Vosevi	Non-Proprietary Name: Sofosbuvir, Velpatasvir, And Voxilaprevir	Tablet, Film Coated	Oral	Gilead Sciences, Inc.	ACTIVE
	71274-170	Joenja	Non-Proprietary Name: Leniolisib	Tablet, Film Coated	Oral	Pharming Healthcare Inc.	ACTIVE
	72626-2701	Sofosbuvir And Velpatasvir	Non-Proprietary Name: Velpatasvir And Sofosbuvir	Tablet, Film Coated	Oral	Asegua Therapeutics Llc	ACTIVE
	73079-050	Zokinvy	Non-Proprietary Name: Lonafarnib	Capsule	Oral	Eiger Biopharmaceuticals, Inc.	ACTIVE
	73079-075	Zokinvy	Non-Proprietary Name: Lonafarnib	Capsule	Oral	Eiger Biopharmaceuticals, Inc.	ACTIVE
	75626-001	Lupkynis	Non-Proprietary Name: Voclosporin	Capsule	Oral	Aurinia Pharma U.s., Inc.	ACTIVE