Programmed Death Receptor-1-directed Antibody Interactions [MoA] - N0000191259

Pharmacologic Code	N0000191259
Pharmacologic Name	Programmed Death Receptor-1-directed Antibody Interactions
Pharmacologic Uses	human programmed death receptor-1 (PD-1)-blocking antibody programmed death receptor-1 (PD-1)-blocking antibody
Pharmacologic Concept	Mechanisms of Action - [MoA]
Pharmacologic Concept Description	This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

The table contains 10 products whose active ingredient are classified under the same pharmacologic class Programmed Death Receptor-1-directed Antibody Interactions [MoA].

	NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
	0003-3734	Opdivo	Non-Proprietary Name: Nivolumab	Injection	Intravenous	E.r. Squibb & Sons, L.l.c.	ACTIVE
	0003-3756	Opdivo	Non-Proprietary Name: Nivolumab	Injection	Intravenous	E.r. Squibb & Sons, L.l.c.	ACTIVE
	0003-3772	Opdivo	Non-Proprietary Name: Nivolumab	Injection	Intravenous	E.r. Squibb & Sons, L.l.c.	ACTIVE
	0003-3774	Opdivo	Non-Proprietary Name: Nivolumab	Injection	Intravenous	E.r. Squibb & Sons, L.l.c.	ACTIVE
	0003-7125	Opdualag	Non-Proprietary Name: Nivolumab And Relatlimab-rmbw	Injection	Intravenous	E.r. Squibb & Sons, L.l.c.	ACTIVE
	0006-3026	Keytruda	Non-Proprietary Name: Pembrolizumab	Injection, Solution	Intravenous	Merck Sharp & Dohme Llc	ACTIVE
	0173-0898	Jemperli	Non-Proprietary Name: Dostarlimab	Injection	Intravenous	Glaxosmithkline Llc	ACTIVE
	50242-917	Tecentriq	Non-Proprietary Name: Atezolizumab	Injection, Solution	Intravenous	Genentech, Inc.	ACTIVE
	50242-918	Tecentriq	Non-Proprietary Name: Atezolizumab	Injection, Solution	Intravenous	Genentech, Inc.	ACTIVE
	50881-006	Zynyz	Non-Proprietary Name: Retifanlimab-dlwr	Injection	Intravenous	Incyte Corporation	ACTIVE