UGT1A1 Inhibitors [MoA] - N0000191272

Pharmacologic Code	N0000191272
Pharmacologic Name	UGT1A1 Inhibitors
Pharmacologic Uses	hepatitis C virus (HCV) NS3/4A protease inhibitor hepatitis C virus (HCV) NS5A inhibitor hepatitis C virus non-nucleoside NS5B palm polymerase inhibitor HIV protease inhibitor kinase inhibitor thrombopoietin receptor agonist
Pharmacologic Concept	Mechanisms of Action - [MoA]
Pharmacologic Concept Description	This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

The table contains 89 products whose active ingredient are classified under the same pharmacologic class UGT1A1 Inhibitors [MoA].

	NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
	0078-0685	Promacta	Non-Proprietary Name: Eltrombopag Olamine	Tablet, Film Coated	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	0078-0697	Promacta	Non-Proprietary Name: Eltrombopag Olamine	Powder, For Suspension	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	0480-3276	Alvaiz	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Teva Pharmaceuticals, Inc.	ACTIVE
	0003-3622	Reyataz	Non-Proprietary Name: Atazanavir	Capsule, Gelatin Coated	Oral	E.r. Squibb & Sons, L.l.c.	ACTIVE
	0003-3641	Evotaz	Non-Proprietary Name: Atazanavir And Cobicistat	Tablet	Oral	E.r. Squibb & Sons, L.l.c.	ACTIVE
	13668-711	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Torrent Pharmaceuticals Limited	ACTIVE
	31722-301	Eltrombopag	Non-Proprietary Name: Eltrombopag Olamine	Powder, For Suspension	Oral	Camber Pharmaceuticals, Inc.	ACTIVE
	70069-840	Eltrombopag Olamine	Non-Proprietary Name: Eltrombopag Olamine	Tablet, Film Coated	Oral	Somerset Therapeutics, Llc	ACTIVE
	70771-1928	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet	Oral	Zydus Lifesciences Limited	ACTIVE
	72865-299	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Xlcare Pharmaceuticals Inc.	ACTIVE
	0078-0526	Tasigna	Non-Proprietary Name: Nilotinib	Capsule	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	60505-3802	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Apotex Corp.	ACTIVE
	72205-157	Eltrombopag	Non-Proprietary Name: Eltrombopag Olamine	Tablet, Film Coated	Oral	Novadoz Pharmaceuticals Llc	ACTIVE
	76282-788	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Exelan Pharmaceuticals Inc.	ACTIVE
	0078-0686	Promacta	Non-Proprietary Name: Eltrombopag Olamine	Tablet, Film Coated	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	24338-154	Danziten	Non-Proprietary Name: Nilotinib	Tablet	Oral	Azurity Pharmaceuticals, Inc.	ACTIVE
	31722-779	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Camber Pharmaceuticals, Inc.	ACTIVE
	43598-055	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Dr. Reddy's Laboratories Inc	ACTIVE
	65862-712		Non-Proprietary Name: Atazanavir	Capsule		Aurobindo Pharma Limited	ACTIVE
	70771-1927	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet	Oral	Zydus Lifesciences Limited	ACTIVE
	0078-0684	Promacta	Non-Proprietary Name: Eltrombopag Olamine	Tablet, Film Coated	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	0078-0951	Tasigna	Non-Proprietary Name: Nilotinib	Capsule	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	42385-920	Atazanavir	Non-Proprietary Name: Atazanavir	Capsule	Oral	Laurus Labs Limited	ACTIVE
	60219-1417	Eltrombopag Olamine	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Amneal Pharmaceuticals Ny Llc	ACTIVE
	70710-1395	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet	Oral	Zydus Pharmaceuticals Usa Inc.	ACTIVE
	72205-158	Eltrombopag	Non-Proprietary Name: Eltrombopag Olamine	Tablet, Film Coated	Oral	Novadoz Pharmaceuticals Llc	ACTIVE
	0480-3274	Alvaiz	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Teva Pharmaceuticals, Inc.	ACTIVE
	65862-710	Atazanavir Sulfate	Non-Proprietary Name: Atazanavir	Capsule	Oral	Aurobindo Pharma Limited	ACTIVE
	70771-1926	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet	Oral	Zydus Lifesciences Limited	ACTIVE
	0078-0972	Promacta	Non-Proprietary Name: Eltrombopag Olamine	Powder, For Suspension	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	31722-780	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Camber Pharmaceuticals, Inc.	ACTIVE
	42385-921	Atazanavir	Non-Proprietary Name: Atazanavir	Capsule	Oral	Laurus Labs Limited	ACTIVE
	60219-1416	Eltrombopag Olamine	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Amneal Pharmaceuticals Ny Llc	ACTIVE
	69097-030	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Cipla Usa Inc.	ACTIVE
	65862-710		Non-Proprietary Name: Atazanavir	Capsule		Aurobindo Pharma Limited	ACTIVE
	72205-159	Eltrombopag	Non-Proprietary Name: Eltrombopag Olamine	Tablet, Film Coated	Oral	Novadoz Pharmaceuticals Llc	ACTIVE
	72205-237	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Novadoz Pharmaceuticals Llc	ACTIVE
	76282-790	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Exelan Pharmaceuticals Inc.	ACTIVE
	0093-5527	Atazanavir Sulfate	Non-Proprietary Name: Atazanavir Sulfate	Capsule	Oral	Teva Pharmaceuticals Usa, Inc.	ACTIVE
	0480-3273	Alvaiz	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Teva Pharmaceuticals, Inc.	ACTIVE
	43598-456	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Dr. Reddy's Laboratories Inc	ACTIVE
	70069-838	Eltrombopag Olamine	Non-Proprietary Name: Eltrombopag Olamine	Tablet, Film Coated	Oral	Somerset Therapeutics, Llc	ACTIVE
	0003-3631	Reyataz	Non-Proprietary Name: Atazanavir	Capsule, Gelatin Coated	Oral	E.r. Squibb & Sons, L.l.c.	ACTIVE
	0093-5528	Atazanavir Sulfate	Non-Proprietary Name: Atazanavir Sulfate	Capsule	Oral	Teva Pharmaceuticals Usa, Inc.	ACTIVE
	31722-654	Atazanavir	Non-Proprietary Name: Atazanavir	Capsule	Oral	Camber Pharmaceuticals, Inc.	ACTIVE
	60219-1414	Eltrombopag Olamine	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Amneal Pharmaceuticals Ny Llc	ACTIVE
	60505-3801	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Apotex Corp.	ACTIVE
	69238-1414	Eltrombopag Olamine	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Amneal Pharmaceuticals Ny Llc	ACTIVE
	69238-1415	Eltrombopag Olamine	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Amneal Pharmaceuticals Ny Llc	ACTIVE
	70069-837	Eltrombopag Olamine	Non-Proprietary Name: Eltrombopag Olamine	Tablet, Film Coated	Oral	Somerset Therapeutics, Llc	ACTIVE
	70710-1396	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet	Oral	Zydus Pharmaceuticals Usa Inc.	ACTIVE
	0003-3638	Reyataz	Non-Proprietary Name: Atazanavir	Powder	Oral	E.r. Squibb & Sons, L.l.c.	ACTIVE
	0074-2625	Mavyret	Non-Proprietary Name: Glecaprevir And Pibrentasvir	Tablet, Film Coated	Oral	Abbvie Inc.	ACTIVE
	31722-655	Atazanavir	Non-Proprietary Name: Atazanavir	Capsule	Oral	Camber Pharmaceuticals, Inc.	ACTIVE
	31722-842	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Camber Pharmaceuticals, Inc.	ACTIVE
	31722-844	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Camber Pharmaceuticals, Inc.	ACTIVE
	43598-455	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Dr. Reddy's Laboratories Inc	ACTIVE
	70771-1925	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet	Oral	Zydus Lifesciences Limited	ACTIVE
	72205-239	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Novadoz Pharmaceuticals Llc	ACTIVE
	76282-789	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Exelan Pharmaceuticals Inc.	ACTIVE
	42385-922	Atazanavir	Non-Proprietary Name: Atazanavir	Capsule	Oral	Laurus Labs Limited	ACTIVE
	65862-713		Non-Proprietary Name: Atazanavir	Capsule		Aurobindo Pharma Limited	ACTIVE
	69097-031	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Cipla Usa Inc.	ACTIVE
	69097-032	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Cipla Usa Inc.	ACTIVE
	69238-1416	Eltrombopag Olamine	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Amneal Pharmaceuticals Ny Llc	ACTIVE
	24338-155	Danziten	Non-Proprietary Name: Nilotinib	Tablet	Oral	Azurity Pharmaceuticals, Inc.	ACTIVE
	60219-1415	Eltrombopag Olamine	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Amneal Pharmaceuticals Ny Llc	ACTIVE
	65862-711	Atazanavir Sulfate	Non-Proprietary Name: Atazanavir	Capsule	Oral	Aurobindo Pharma Limited	ACTIVE
	65862-712	Atazanavir Sulfate	Non-Proprietary Name: Atazanavir	Capsule	Oral	Aurobindo Pharma Limited	ACTIVE
	70069-839	Eltrombopag Olamine	Non-Proprietary Name: Eltrombopag Olamine	Tablet, Film Coated	Oral	Somerset Therapeutics, Llc	ACTIVE
	70710-1397	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet	Oral	Zydus Pharmaceuticals Usa Inc.	ACTIVE
	0074-2600	Mavyret	Non-Proprietary Name: Glecaprevir And Pibrentasvir	Pellet	Oral	Abbvie Inc.	ACTIVE
	0078-0592	Tasigna	Non-Proprietary Name: Nilotinib	Capsule	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	0093-5526	Atazanavir Sulfate	Non-Proprietary Name: Atazanavir Sulfate	Capsule	Oral	Teva Pharmaceuticals Usa, Inc.	ACTIVE
	13668-710	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Torrent Pharmaceuticals Limited	ACTIVE
	31722-300	Eltrombopag	Non-Proprietary Name: Eltrombopag Olamine	Powder, For Suspension	Oral	Camber Pharmaceuticals, Inc.	ACTIVE
	31722-843	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Camber Pharmaceuticals, Inc.	ACTIVE
	72205-156	Eltrombopag	Non-Proprietary Name: Eltrombopag Olamine	Tablet, Film Coated	Oral	Novadoz Pharmaceuticals Llc	ACTIVE
	72205-238	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Novadoz Pharmaceuticals Llc	ACTIVE
	72865-301	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Xlcare Pharmaceuticals Inc.	ACTIVE
	0480-3275	Alvaiz	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Teva Pharmaceuticals, Inc.	ACTIVE
	31722-841	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Camber Pharmaceuticals, Inc.	ACTIVE
	70710-1398	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet	Oral	Zydus Pharmaceuticals Usa Inc.	ACTIVE
	72865-302	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Xlcare Pharmaceuticals Inc.	ACTIVE
	0078-0687	Promacta	Non-Proprietary Name: Eltrombopag Olamine	Tablet, Film Coated	Oral	Novartis Pharmaceuticals Corporation	ACTIVE
	31722-653	Atazanavir	Non-Proprietary Name: Atazanavir	Capsule	Oral	Camber Pharmaceuticals, Inc.	ACTIVE
	50419-171	Stivarga	Non-Proprietary Name: Regorafenib	Tablet, Film Coated	Oral	Bayer Healthcare Pharmaceuticals Inc.	ACTIVE
	60505-3803	Nilotinib	Non-Proprietary Name: Nilotinib	Capsule	Oral	Apotex Corp.	ACTIVE
	65597-407	Turalio	Non-Proprietary Name: Pexidartinib Hydrochloride	Capsule	Oral	Daiichi Sankyo Inc.	ACTIVE
	65862-711		Non-Proprietary Name: Atazanavir	Capsule		Aurobindo Pharma Limited	ACTIVE
	65862-713	Atazanavir Sulfate	Non-Proprietary Name: Atazanavir	Capsule	Oral	Aurobindo Pharma Limited	ACTIVE
	69238-1417	Eltrombopag Olamine	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Amneal Pharmaceuticals Ny Llc	ACTIVE
	72865-300	Eltrombopag	Non-Proprietary Name: Eltrombopag	Tablet, Film Coated	Oral	Xlcare Pharmaceuticals Inc.	ACTIVE