Antisense Oligonucleotide [EPC] - N0000191626

Pharmacologic Class Information

Pharmacologic Code N0000191626
Pharmacologic Name Antisense Oligonucleotide
Pharmacologic Uses
  • antisense oligonucleotide
  • apolipoprotein B-100 synthesis inhibitor
  • survival motor neuron-2 (SMN2)-directed antisense oligonucleotide
  • transthyretin-directed antisense oligonucleotide
Pharmacologic Concept Established Pharmacologic Classes - [EPC]
Pharmacologic Concept Description An established pharmacologic class is a term or phrase that is scientifically valid and clinically meaningful according to the following definitions:
  • A scientifically valid pharmacologic class is supported by documented and submitted empiric evidence showing that the drug's pharmacologic class is known, not theoretical, and relevant and specific to the indication.
  • A clinically meaningful pharmacologic class term or phrase enhances the ability of professionals to understand physiologic effects related to the indication or to anticipate undesirable effects that may be associated with the drug or pharmacologic class.

NDC Products with Antisense Oligonucleotide

The table contains 6 products whose active ingredient are classified under the same pharmacologic class Antisense Oligonucleotide [EPC].

NDC Proprietary Name Non-Proprietary Name Dosage Form Route Name Company Name Status
60923-227Amondys 45 Non-Proprietary Name: CasimersenInjectionIntravenousSarepta Therapeutics, Inc.ACTIVE
60923-284Exondys 51 Non-Proprietary Name: EteplirsenInjectionIntravenousSarepta Therapeutics, Inc.ACTIVE
60923-363Exondys 51 Non-Proprietary Name: EteplirsenInjectionIntravenousSarepta Therapeutics, Inc.ACTIVE
60923-465Vyondys 53 Non-Proprietary Name: GolodirsenInjectionIntravenousSarepta Therapeutics, Inc.ACTIVE
64406-058Spinraza Non-Proprietary Name: NusinersenInjection, SolutionIntrathecalBiogenACTIVE
72126-007Tegsedi Non-Proprietary Name: InotersenInjection, SolutionSubcutaneousAkcea Therapeutics, Inc.ACTIVE