Vascular Endothelial Growth Factor Inhibitor [EPC] - N0000193543

Pharmacologic Code	N0000193543
Pharmacologic Name	Vascular Endothelial Growth Factor Inhibitor
Pharmacologic Uses	vascular endothelial growth factor (VEGF) inhibitor vascular endothelial growth factor-specific angiogenesis inhibitor
Pharmacologic Concept	Established Pharmacologic Classes - [EPC]
Pharmacologic Concept Description	An established pharmacologic class is a term or phrase that is scientifically valid and clinically meaningful according to the following definitions: A scientifically valid pharmacologic class is supported by documented and submitted empiric evidence showing that the drug's pharmacologic class is known, not theoretical, and relevant and specific to the indication. A clinically meaningful pharmacologic class term or phrase enhances the ability of professionals to understand physiologic effects related to the indication or to anticipate undesirable effects that may be associated with the drug or pharmacologic class.

The table contains 21 products whose active ingredient are classified under the same pharmacologic class Vascular Endothelial Growth Factor Inhibitor [EPC].

	NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
	0024-5840	Zaltrap	Non-Proprietary Name: Ziv-aflibercept	Solution, Concentrate	Intravenous	Sanofi-aventis U.s. Llc	ACTIVE
	0024-5841	Zaltrap	Non-Proprietary Name: Ziv-aflibercept	Solution, Concentrate	Intravenous	Sanofi-aventis U.s. Llc	ACTIVE
	0069-0315	Zirabev	Non-Proprietary Name: Bevacizumab-bvzr	Injection, Solution	Intravenous	Pfizer Laboratories Div Pfizer Inc	ACTIVE
	0069-0342	Zirabev	Non-Proprietary Name: Bevacizumab-bvzr	Injection, Solution	Intravenous	Pfizer Laboratories Div Pfizer Inc	ACTIVE
	50242-060	Avastin	Non-Proprietary Name: Bevacizumab	Injection, Solution	Intravenous	Genentech, Inc.	ACTIVE
	50242-061	Avastin	Non-Proprietary Name: Bevacizumab	Injection, Solution	Intravenous	Genentech, Inc.	ACTIVE
	50242-078	Susvimo	Non-Proprietary Name: Ranibizumab	Injection, Solution	Intravitreal	Genentech, Inc.	ACTIVE
	50242-080	Lucentis	Non-Proprietary Name: Ranibizumab	Injection, Solution	Intravitreal	Genentech, Inc.	ACTIVE
	50242-082	Lucentis	Non-Proprietary Name: Ranibizumab	Injection, Solution	Intravitreal	Genentech, Inc.	ACTIVE
	55513-206	Mvasi	Non-Proprietary Name: Bevacizumab-awwb	Injection, Solution	Intravenous	Amgen Inc	ACTIVE
	55513-207	Mvasi	Non-Proprietary Name: Bevacizumab-awwb	Injection, Solution	Intravenous	Amgen Inc	ACTIVE
	61755-005	Eylea	Non-Proprietary Name: Aflibercept	Injection, Solution	Intravitreal	Regeneron Pharmaceuticals, Inc.	ACTIVE
	61755-050	Eylea Hd	Non-Proprietary Name: Aflibercept	Injection, Solution	Intravitreal	Regeneron Pharmaceuticals, Inc	ACTIVE
	61755-051	Eylea Hd	Non-Proprietary Name: Aflibercept	Injection, Solution	Intravitreal	Regeneron Pharmaceuticals, Inc	ACTIVE
	64406-019	Byooviz	Non-Proprietary Name: Ranibizumab-nuna	Injection, Solution	Intravitreal	Biogen Inc.	ACTIVE
	70114-440	Cimerli	Non-Proprietary Name: Ranibizumab-eqrn	Injection, Solution	Intravitreal	Coherus Biosciences Inc	ACTIVE
	70114-441	Cimerli	Non-Proprietary Name: Ranibizumab-eqrn	Injection, Solution	Intravitreal	Coherus Biosciences Inc	ACTIVE
	70121-1754	Alymsys	Non-Proprietary Name: Bevacizumab-maly	Injection, Solution	Intravenous	Amneal Pharmaceuticals Llc	ACTIVE
	70121-1755	Alymsys	Non-Proprietary Name: Bevacizumab-maly	Injection, Solution	Intravenous	Amneal Pharmaceuticals Llc	ACTIVE
	72606-011	Vegzelma	Non-Proprietary Name: Bevacizumab-adcd	Injection, Solution	Intravenous	Celltrion Usa, Inc.	ACTIVE
	72606-012	Vegzelma	Non-Proprietary Name: Bevacizumab-adcd	Injection, Solution	Intravenous	Celltrion Usa, Inc.	ACTIVE