Tropomyosin Receptor Kinases Inhibitors [MoA] - N0000193859

Pharmacologic Code	N0000193859
Pharmacologic Name	Tropomyosin Receptor Kinases Inhibitors
Pharmacologic Uses	kinase inhibitor
Pharmacologic Concept	Mechanisms of Action - [MoA]
Pharmacologic Concept Description	This concept refers to the mechanism of action pharmacologic action at the receptor, membrane, or tissue level. In MED-RT, molecular, subcellular, or cellular effects of drug generic ingredients, organized into a chemical function classification hierarchy, beneath the "Cellular or Molecular Interactions" concept.

The table contains 7 products whose active ingredient are classified under the same pharmacologic class Tropomyosin Receptor Kinases Inhibitors [MoA].

	NDC	Proprietary Name	Non-Proprietary Name	Dosage Form	Route Name	Company Name	Status
	50419-390	Vitrakvi	Non-Proprietary Name: Larotrectinib	Capsule	Oral	Bayer Healthcare Pharmaceuticals Inc.	ACTIVE
	50419-392	Vitrakvi	Non-Proprietary Name: Larotrectinib	Solution, Concentrate	Oropharyngeal	Bayer Healthcare Pharmaceuticals Inc.	ACTIVE
	50419-391	Vitrakvi	Non-Proprietary Name: Larotrectinib	Capsule	Oral	Bayer Healthcare Pharmaceuticals Inc.	ACTIVE
	50419-393	Vitrakvi	Non-Proprietary Name: Larotrectinib	Solution, Concentrate	Oropharyngeal	Bayer Healthcare Pharmaceuticals Inc.	ACTIVE
	71777-390	Vitrakvi	Non-Proprietary Name: Larotrectinib	Capsule	Oral	Loxo Oncology, Inc.	ACTIVE
	71777-391	Vitrakvi	Non-Proprietary Name: Larotrectinib	Capsule	Oral	Loxo Oncology, Inc.	ACTIVE
	71777-392	Vitrakvi	Non-Proprietary Name: Larotrectinib	Solution	Oral	Loxo Oncology, Inc.	ACTIVE