Pheniramine maleate 16 mg / phenylpropanolamine hydrochloride 50 mg / phenyltoloxamine citrate 16 mg / pyrilamine maleate 16 mg Extended Release Oral Capsule [Histine D]
RxNorm 1037074

Concept Hierarchy & Relationship Mapping

RxNorm Concept Unique Identifier (RxCUI) 1037074 represents a standardized clinical drug concept used for cross-system interoperability. This concept aggregates multiple Atom IDs (AUIs), which are specific naming variations and synonyms used across pharmaceutical databases to ensure accurate medication mapping for: pheniramine maleate 16 mg / phenylpropanolamine hydrochloride 50 mg / phenyltoloxamine citrate 16 mg / pyrilamine maleate 16 mg Extended Release Oral Capsule [Histine D].

The following semantic concepts and normalized strings are associated with this clinical entity:

SY
Histine-D (pheniramine maleate 16 mg / phenylpropanolamine hydrochloride 50 mg / phenyltoloxamine citrate 16 mg / pyrilamine maleate 16 mg) Extended Release Oral Capsule
AUI:6353732
View
SBD
Pheniramine maleate 16 mg / phenylpropanolamine hydrochloride 50 mg / phenyltoloxamine citrate 16 mg / pyrilamine maleate 16 mg Extended Release Oral Capsule [Histine D]
AUI:12370939
View

This clinical crossover tool is designed for healthcare professionals, pharmacists, and data analysts to safely compare substitute products and manage medication interoperability.

SY

Synonym (SY):
Histine-D (pheniramine maleate 16 mg / phenylpropanolamine hydrochloride 50 mg / phenyltoloxamine citrate 16 mg / pyrilamine maleate 16 mg) Extended Release Oral Capsule
(Atom ID: 6353732)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
Histine-D (pheniramine maleate 16 MG / phenylpropanolamine hydrochloride 50 MG / phenyltoloxamine citrate 16 MG / pyrilamine maleate 16 MG) Extended Release Oral Capsule
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
1037074
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
6353732
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SY
Synonym (Synonym of another TTY, given for clarity.)
Source Code
1037074
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
SBD

Semantic Branded Drug (SBD):
Pheniramine maleate 16 mg / phenylpropanolamine hydrochloride 50 mg / phenyltoloxamine citrate 16 mg / pyrilamine maleate 16 mg Extended Release Oral Capsule [Histine D]
(Atom ID: 12370939)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
pheniramine maleate 16 MG / phenylpropanolamine hydrochloride 50 MG / phenyltoloxamine citrate 16 MG / pyrilamine maleate 16 MG Extended Release Oral Capsule [Histine D]
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
1037074
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12370939
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SBD
Semantic Branded Drug (Ingredient + Strength + Dose Form + Brand Name)
Source Code
1037074
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

Technical Attributes & Logic

RXN AI
{1037066} 266959
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AI
{1037067} 3266
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AI
{1037068} 221141
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AI
{1037069} 82091
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AM
{1037066} 8132
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN AM
{1037067} 8175
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN AM
{1037068} 33408
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN AM
{1037069} 9009
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{1037066} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{1037067} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{1037068} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{1037069} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN OBSOLETED
04/30/2020
Date the RxNorm atom became obsolete