RxNorm 1442981

Ibrutinib

RxNorm Semantic Concepts

RxNorm semantic concepts for the RxCUI 1442981 unique identifier include: ibrutinib (12251449), Ibrutinib (7262233), Ibrutinib (substance) (7262234), Product containing ibrutinib (medicinal product) (10307209) and Ibrutinib-containing product (10804818).

RxNorm Atom ID: 12251449 - Ingredient
ibrutinib

RXCUI:
1442981 - RxNorm Unique Identifier for a concept (Concept ID)
LAT:
ENG - Language of the Term
RXAUI:
12251449 - Unique identifier for the atom (RxNorm Atom ID)
Is Prescribable?
YES - This drug is part of the RxNorm Current Prescribable Content, a subset of RxNorm that includes all drugs available for prescription in the United States. The Current Prescribable subset also includes over-the-counter drugs.
Concept Description:
ibrutinib - Description of concept identifier
Term Type (TTY):
IN - Term type in source with name and description
Term Type Name:
Ingredient - Name of term type in source
Term Type Description:
A compound or moiety that gives the drug its distinctive clinical properties. Ingredients generally use the United States Adopted Name (USAN). - Description of term type in source
Code:
1442981 - "Most useful" source asserted identifier. If the source vocabulary has more than one identifier, or a RxNorm-generated source entry identifier. (if the source vocabulary has none.)
Suppress Flag:
N
Suppressible flag. Values = N, O, Y, or E. N - not suppressible. O - Specific individual names (atoms) set as Obsolete because the name is no longer provided by the original source. Y - Suppressed by RxNorm editor. E - unquantified, non-prescribable drug with related quantified, prescribable drugs. NLM strongly recommends that users not alter editor-assigned suppressibility.
CVF:
4096 - Content view flag. RxNorm includes one value, '4096', to denote inclusion in the Current Prescribable Content subset. All rows with CVF='4096' can be found in the subset.
RxNorm to UNII Crosswalk:
1X70OSD4VX - IBRUTINIB (C(C=C)(=O)N1C[C@@H](CCC1)n2nc(c3c2ncnc3N)-c4ccc(cc4)Oc5ccccc5) - RxNorm to UNII (Unique Ingredient Identifier) Crosswalk
Source:
RXNORM - Concept source abbreviation
Source Name:
RxNorm Vocabulary - The official name for a source
Source Version:
20AA_240304F - The source version
Source Date:
March 04, 2024 - RxNorm data last updated
Source License Contact:
RxNorm Customer Service

U.S. National Library of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
(888) FIND-NLM

[email protected]
https://www.nlm.nih.gov/research/umls/rxnorm/ - The source license contact information
Source Content Contact:
RxNorm Customer Service

U.S. National Library of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
(888) FIND-NLM

[email protected]
https://www.nlm.nih.gov/research/umls/rxnorm/ - The source content contact information
Source Short Name:
RxNorm work done by the National Library of Medicine - The short name of a source as used by the NLM Knowledge Source Server

RxNorm Atom ID: 7262233 - Designated preferred name
Ibrutinib

RXCUI:
1442981 - RxNorm Unique Identifier for a concept (Concept ID)
LAT:
ENG - Language of the Term
RXAUI:
7262233 - Unique identifier for the atom (RxNorm Atom ID)
Is Prescribable?
YES - This drug is part of the RxNorm Current Prescribable Content, a subset of RxNorm that includes all drugs available for prescription in the United States. The Current Prescribable subset also includes over-the-counter drugs.
Concept Description:
Ibrutinib - Description of concept identifier
Term Type (TTY):
PT - Term type in source with name and description
Term Type Name:
Designated preferred name - Name of term type in source
Term Type Description:
- Description of term type in source
Code:
710228002 - "Most useful" source asserted identifier. If the source vocabulary has more than one identifier, or a RxNorm-generated source entry identifier. (if the source vocabulary has none.)
Suppress Flag:
N
Suppressible flag. Values = N, O, Y, or E. N - not suppressible. O - Specific individual names (atoms) set as Obsolete because the name is no longer provided by the original source. Y - Suppressed by RxNorm editor. E - unquantified, non-prescribable drug with related quantified, prescribable drugs. NLM strongly recommends that users not alter editor-assigned suppressibility.
CVF:
- Content view flag. RxNorm includes one value, '4096', to denote inclusion in the Current Prescribable Content subset. All rows with CVF='4096' can be found in the subset.
RxNorm to UNII Crosswalk:
1X70OSD4VX - IBRUTINIB (C(C=C)(=O)N1C[C@@H](CCC1)n2nc(c3c2ncnc3N)-c4ccc(cc4)Oc5ccccc5) - RxNorm to UNII (Unique Ingredient Identifier) Crosswalk
Source:
SNOMEDCT_US - Concept source abbreviation
Source Name:
US Edition of SNOMED CT - The official name for a source
Source Version:
2024_01_01 - The source version
Source Date:
March 04, 2024 - RxNorm data last updated
Source License Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source license contact information
Source Content Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library Of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source content contact information
Source Short Name:
US Edition of SNOMED CT - The short name of a source as used by the NLM Knowledge Source Server

RxNorm Atom ID: 7262234 - Full form of descriptor
Ibrutinib (substance)

RXCUI:
1442981 - RxNorm Unique Identifier for a concept (Concept ID)
LAT:
ENG - Language of the Term
RXAUI:
7262234 - Unique identifier for the atom (RxNorm Atom ID)
Is Prescribable?
YES - This drug is part of the RxNorm Current Prescribable Content, a subset of RxNorm that includes all drugs available for prescription in the United States. The Current Prescribable subset also includes over-the-counter drugs.
Concept Description:
Ibrutinib (substance) - Description of concept identifier
Term Type (TTY):
FN - Term type in source with name and description
Term Type Name:
Full form of descriptor - Name of term type in source
Term Type Description:
- Description of term type in source
Code:
710228002 - "Most useful" source asserted identifier. If the source vocabulary has more than one identifier, or a RxNorm-generated source entry identifier. (if the source vocabulary has none.)
Suppress Flag:
N
Suppressible flag. Values = N, O, Y, or E. N - not suppressible. O - Specific individual names (atoms) set as Obsolete because the name is no longer provided by the original source. Y - Suppressed by RxNorm editor. E - unquantified, non-prescribable drug with related quantified, prescribable drugs. NLM strongly recommends that users not alter editor-assigned suppressibility.
CVF:
- Content view flag. RxNorm includes one value, '4096', to denote inclusion in the Current Prescribable Content subset. All rows with CVF='4096' can be found in the subset.
RxNorm to UNII Crosswalk:
1X70OSD4VX - IBRUTINIB (C(C=C)(=O)N1C[C@@H](CCC1)n2nc(c3c2ncnc3N)-c4ccc(cc4)Oc5ccccc5) - RxNorm to UNII (Unique Ingredient Identifier) Crosswalk
Source:
SNOMEDCT_US - Concept source abbreviation
Source Name:
US Edition of SNOMED CT - The official name for a source
Source Version:
2024_01_01 - The source version
Source Date:
March 04, 2024 - RxNorm data last updated
Source License Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source license contact information
Source Content Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library Of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source content contact information
Source Short Name:
US Edition of SNOMED CT - The short name of a source as used by the NLM Knowledge Source Server

RxNorm Atom ID: 10307209 - Full form of descriptor
Product containing ibrutinib (medicinal product)

RXCUI:
1442981 - RxNorm Unique Identifier for a concept (Concept ID)
LAT:
ENG - Language of the Term
RXAUI:
10307209 - Unique identifier for the atom (RxNorm Atom ID)
Is Prescribable?
YES - This drug is part of the RxNorm Current Prescribable Content, a subset of RxNorm that includes all drugs available for prescription in the United States. The Current Prescribable subset also includes over-the-counter drugs.
Concept Description:
Product containing ibrutinib (medicinal product) - Description of concept identifier
Term Type (TTY):
FN - Term type in source with name and description
Term Type Name:
Full form of descriptor - Name of term type in source
Term Type Description:
- Description of term type in source
Code:
715598009 - "Most useful" source asserted identifier. If the source vocabulary has more than one identifier, or a RxNorm-generated source entry identifier. (if the source vocabulary has none.)
Suppress Flag:
N
Suppressible flag. Values = N, O, Y, or E. N - not suppressible. O - Specific individual names (atoms) set as Obsolete because the name is no longer provided by the original source. Y - Suppressed by RxNorm editor. E - unquantified, non-prescribable drug with related quantified, prescribable drugs. NLM strongly recommends that users not alter editor-assigned suppressibility.
CVF:
- Content view flag. RxNorm includes one value, '4096', to denote inclusion in the Current Prescribable Content subset. All rows with CVF='4096' can be found in the subset.
RxNorm to UNII Crosswalk:
1X70OSD4VX - IBRUTINIB (C(C=C)(=O)N1C[C@@H](CCC1)n2nc(c3c2ncnc3N)-c4ccc(cc4)Oc5ccccc5) - RxNorm to UNII (Unique Ingredient Identifier) Crosswalk
Source:
SNOMEDCT_US - Concept source abbreviation
Source Name:
US Edition of SNOMED CT - The official name for a source
Source Version:
2024_01_01 - The source version
Source Date:
March 04, 2024 - RxNorm data last updated
Source License Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source license contact information
Source Content Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library Of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source content contact information
Source Short Name:
US Edition of SNOMED CT - The short name of a source as used by the NLM Knowledge Source Server

RxNorm Atom ID: 10804818 - Designated preferred name
Ibrutinib-containing product

RXCUI:
1442981 - RxNorm Unique Identifier for a concept (Concept ID)
LAT:
ENG - Language of the Term
RXAUI:
10804818 - Unique identifier for the atom (RxNorm Atom ID)
Is Prescribable?
YES - This drug is part of the RxNorm Current Prescribable Content, a subset of RxNorm that includes all drugs available for prescription in the United States. The Current Prescribable subset also includes over-the-counter drugs.
Concept Description:
Ibrutinib-containing product - Description of concept identifier
Term Type (TTY):
PT - Term type in source with name and description
Term Type Name:
Designated preferred name - Name of term type in source
Term Type Description:
- Description of term type in source
Code:
715598009 - "Most useful" source asserted identifier. If the source vocabulary has more than one identifier, or a RxNorm-generated source entry identifier. (if the source vocabulary has none.)
Suppress Flag:
N
Suppressible flag. Values = N, O, Y, or E. N - not suppressible. O - Specific individual names (atoms) set as Obsolete because the name is no longer provided by the original source. Y - Suppressed by RxNorm editor. E - unquantified, non-prescribable drug with related quantified, prescribable drugs. NLM strongly recommends that users not alter editor-assigned suppressibility.
CVF:
- Content view flag. RxNorm includes one value, '4096', to denote inclusion in the Current Prescribable Content subset. All rows with CVF='4096' can be found in the subset.
RxNorm to UNII Crosswalk:
1X70OSD4VX - IBRUTINIB (C(C=C)(=O)N1C[C@@H](CCC1)n2nc(c3c2ncnc3N)-c4ccc(cc4)Oc5ccccc5) - RxNorm to UNII (Unique Ingredient Identifier) Crosswalk
Source:
SNOMEDCT_US - Concept source abbreviation
Source Name:
US Edition of SNOMED CT - The official name for a source
Source Version:
2024_01_01 - The source version
Source Date:
March 04, 2024 - RxNorm data last updated
Source License Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source license contact information
Source Content Contact:
National Library Of Medicine
NLM is a Charter Member of SNOMED International on behalf of the U.S.
National Library Of Medicine
8600 Rockville Pike

Bethesda
MD
United States
20894
1-888-FIND-NLM (1-888-346-3656)

https://support.nlm.nih.gov/support/create-case/
- The source content contact information
Source Short Name:
US Edition of SNOMED CT - The short name of a source as used by the NLM Knowledge Source Server

* This product uses publicly available data courtesy of the U.S. National Library of Medicine (NLM), National Institutes of Health, Department of Health and Human Services; NLM is not responsible for the product and does not endorse or recommend this or any other product.

Patient Education

Ibrutinib


Ibrutinib is used: to treat people with mantle cell lymphoma (MCL; a fast-growing cancer that begins in the cells of the immune system) who have already been treated with at least one other chemotherapy medication, to treat people with chronic lymphocytic leukemia (CLL; a type of cancer that begins in the white blood cells) and small lymphocytic lymphoma (SLL; a type of cancer that begins mostly in the lymph nodes), to treat people with Waldenstrom's macroglobulinemia (WM; a slow-growing cancer that begins in certain white blood cells in your bone marrow), to treat people with marginal zone lymphoma (MZL; a slow growing cancer that begins in a type of white blood cells that normally fights infection) who have already been treated with a certain type of chemotherapy medication, and to treat people with chronic graft vs host disease (cGVHD; a complication of hematopoietic stem-cell transplant [HSCT; a procedure that replaces diseased bone marrow with healthy bone marrow] that may start a while after the transplant and last for a long time) after being treated unsuccessfully with 1 or more medications. Ibrutinib is in a class of medications called kinase inhibitors. It works by blocking the action of the abnormal protein that signals cancer cells to multiply. This helps stop the spread of cancer cells.
[Learn More]


Cancer Chemotherapy


Normally, your cells grow and die in a controlled way. Cancer cells keep growing without control. Chemotherapy is drug therapy for cancer. It works by killing the cancer cells, stopping them from spreading, or slowing their growth. However, it can also harm healthy cells, which causes side effects.

You may have a lot of side effects, some, or none at all. It depends on the type and amount of chemotherapy you get and how your body reacts. Some common side effects are fatigue, nausea, vomiting, pain, and hair loss. There are ways to prevent or control some side effects. Talk with your health care provider about how to manage them. Healthy cells usually recover after chemotherapy is over, so most side effects gradually go away.

Your treatment plan will depend on the cancer type, the chemotherapy drugs used, the treatment goal, and how your body responds. Chemotherapy may be given alone or with other treatments. You may get treatment every day, every week, or every month. You may have breaks between treatments so that your body has a chance to build new healthy cells. You might take the drugs by mouth, in a shot, as a cream, or intravenously (by IV).

NIH: National Cancer Institute


[Learn More]


* Please review the disclaimer below.