Lofexidine 0.18 mg
RxNorm 2046590

Concept Hierarchy & Relationship Mapping

RxNorm Concept Unique Identifier (RxCUI) 2046590 represents a standardized clinical drug concept used for cross-system interoperability. This concept aggregates multiple Atom IDs (AUIs), which are specific naming variations and synonyms used across pharmaceutical databases to ensure accurate medication mapping for: lofexidine 0.18 mg.

The following semantic concepts and normalized strings are associated with this clinical entity:

SCDC
Lofexidine 0.18 mg
AUI:10274878
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This clinical crossover tool is designed for healthcare professionals, pharmacists, and data analysts to safely compare substitute products and manage medication interoperability.

SCDCPrescribable

Semantic Clinical Drug Component (SCDC):
Lofexidine 0.18 mg
(Atom ID: 10274878)

Clinical Status & Identity

Prescribable Status
YES (Active)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
lofexidine 0.18 MG
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
2046590
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
10274878
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SCDC
Semantic Clinical Drug Component (Ingredient + Strength)
Source Code
2046590
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

Technical Attributes & Logic

RXN BOSS STRENGTH DENOM UNIT
1
RXN Boss Strength Denom Unit
RXN BOSS STRENGTH DENOM VALUE
1
RXN Boss Strength Denom Value
RXN BOSS STRENGTH NUM UNIT
MG
RXN Boss Strength Num Unit
RXN BOSS STRENGTH NUM VALUE
0.18
RXN Boss Strength Num Value
RXN STRENGTH
0.18 MG
Strength plus unit of SCDC

Patient Education

Lofexidine


Lofexidine is used to manage opioid withdrawal symptoms (e.g., sick feeling, stomach cramps, muscle spasms or twitching, cold sensation, heart pounding, muscle tension, aches and pains, yawning, runny eyes, or difficulty falling asleep or staying asleep) that may occur after an opioid medication is suddenly stopped. Lofexidine is in a class of medications called central alpha adrenergic agonists. It works by relaxing blood vessels so that blood can flow more easily through the body.
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