Acetaminophen 325 mg / chlorpheniramine maleate 8 mg / phenylephrine HCl 40 mg / phenyltoloxamine citrate 50 mg 12HR Extended Release Oral Tablet
RxNorm 2184131

Concept Hierarchy & Relationship Mapping

RxNorm Concept Unique Identifier (RxCUI) 2184131 represents a standardized clinical drug concept used for cross-system interoperability. This concept aggregates multiple Atom IDs (AUIs), which are specific naming variations and synonyms used across pharmaceutical databases to ensure accurate medication mapping for: acetaminophen 325 mg / chlorpheniramine maleate 8 mg / phenylephrine HCl 40 mg / phenyltoloxamine citrate 50 mg 12HR Extended Release Oral Tablet.

The following semantic concepts and normalized strings are associated with this clinical entity:

SCD
12 HR acetaminophen 325 mg / chlorpheniramine maleate 8 mg / phenylephrine hydrochloride 40 mg / phenyltoloxamine citrate 50 mg Extended Release Oral Tablet
Primary clinical definition
AUI:12335360
View
SY
12 HR APAP 325 mg / chlorpheniramine maleate 8 mg / phenylephrine HCl 40 mg / phenyltoloxamine citrate 50 mg Extended Release Oral Tablet
AUI:11442154
View
SY
12 HR APAP 325 mg / Chlorpheniramine Maleate 8 mg / Phenylephrine Hydrochloride 40 mg / Phenyltoloxamine citrate 50 mg Extended Release Oral Tablet
AUI:11442998
View
SY
Acetaminophen 325 mg / chlorpheniramine maleate 8 mg / phenylephrine HCl 40 mg / phenyltoloxamine citrate 50 mg 12 HR Extended Release Oral Tablet
AUI:11442155
View
PSN
Acetaminophen 325 mg / chlorpheniramine maleate 8 mg / phenylephrine HCl 40 mg / phenyltoloxamine citrate 50 mg 12HR Extended Release Oral Tablet
AUI:11442153
View

This clinical crossover tool is designed for healthcare professionals, pharmacists, and data analysts to safely compare substitute products and manage medication interoperability.

SCD

Semantic Clinical Drug (SCD):
12 HR acetaminophen 325 mg / chlorpheniramine maleate 8 mg / phenylephrine hydrochloride 40 mg / phenyltoloxamine citrate 50 mg Extended Release Oral Tablet
(Atom ID: 12335360)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
12 HR acetaminophen 325 MG / chlorpheniramine maleate 8 MG / phenylephrine hydrochloride 40 MG / phenyltoloxamine citrate 50 MG Extended Release Oral Tablet
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
2184131
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12335360
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SCD
Semantic Clinical Drug (Ingredient + Strength + Dose Form)
Source Code
2184131
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

Technical Attributes & Logic

RXN AI
{1012763} 8164
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AI
{315263} 161
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AI
{857648} 142429
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AI
{998720} 221141
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AM
{1012763} 8163
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN AM
{315263} 161
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN AM
{857648} 2400
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN AM
{998720} 33408
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{1012763} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{315263} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{857648} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{998720} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN OBSOLETED
04/30/2020
Date the RxNorm atom became obsolete
RXN QUANTITY
12 HR
Normal Form quantity factor
SY

Synonym (SY):
12 HR APAP 325 mg / chlorpheniramine maleate 8 mg / phenylephrine HCl 40 mg / phenyltoloxamine citrate 50 mg Extended Release Oral Tablet
(Atom ID: 11442154)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
12 HR APAP 325 MG / chlorpheniramine maleate 8 MG / phenylephrine HCl 40 MG / phenyltoloxamine citrate 50 MG Extended Release Oral Tablet
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
2184131
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
11442154
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SY
Synonym (Synonym of another TTY, given for clarity.)
Source Code
2184131
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
SY

Synonym (SY):
12 HR APAP 325 mg / Chlorpheniramine Maleate 8 mg / Phenylephrine Hydrochloride 40 mg / Phenyltoloxamine citrate 50 mg Extended Release Oral Tablet
(Atom ID: 11442998)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
12 HR APAP 325 MG / Chlorpheniramine Maleate 8 MG / Phenylephrine Hydrochloride 40 MG / Phenyltoloxamine citrate 50 MG Extended Release Oral Tablet
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
2184131
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
11442998
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SY
Synonym (Synonym of another TTY, given for clarity.)
Source Code
2184131
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
SY

Synonym (SY):
Acetaminophen 325 mg / chlorpheniramine maleate 8 mg / phenylephrine HCl 40 mg / phenyltoloxamine citrate 50 mg 12 HR Extended Release Oral Tablet
(Atom ID: 11442155)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
acetaminophen 325 MG / chlorpheniramine maleate 8 MG / phenylephrine HCl 40 MG / phenyltoloxamine citrate 50 MG 12 HR Extended Release Oral Tablet
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
2184131
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
11442155
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SY
Synonym (Synonym of another TTY, given for clarity.)
Source Code
2184131
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
PSN

Prescribable Name (PSN):
Acetaminophen 325 mg / chlorpheniramine maleate 8 mg / phenylephrine HCl 40 mg / phenyltoloxamine citrate 50 mg 12HR Extended Release Oral Tablet
(Atom ID: 11442153)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
acetaminophen 325 MG / chlorpheniramine maleate 8 MG / phenylephrine HCl 40 MG / phenyltoloxamine citrate 50 MG 12HR Extended Release Oral Tablet
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
2184131
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
11442153
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
PSN
Prescribable Name (Synonym of another TTY, given for clarity and for display purposes in electronic prescribing applications. Only one PSN per concept.)
Source Code
2184131
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.