Glibenclamide- and metformin-containing product
RxNorm 285129
Concept Hierarchy & Relationship Mapping
RxNorm Concept Unique Identifier (RxCUI) 285129 represents a standardized clinical drug concept used for cross-system interoperability. This concept aggregates multiple Atom IDs (AUIs), which are specific naming variations and synonyms used across pharmaceutical databases to ensure accurate medication mapping for: Glibenclamide- and metformin-containing product.
The following semantic concepts and normalized strings are associated with this clinical entity:
This clinical crossover tool is designed for healthcare professionals, pharmacists, and data analysts to safely compare substitute products and manage medication interoperability.
Synonym (SY):
Glibenclamide- and metformin-containing product
(Atom ID: 10803665)
Tall Man Lettering Synonym (TMSY):
GlyBURIDE / metFORMIN
(Atom ID: 3742874)
Multiple Ingredients (MIN):
Glyburide / metformin
(Atom ID: 12351253)
Designated preferred name (PT):
Glyburide- and metformin-containing product
(Atom ID: 10803760)
Full form of descriptor (FN):
Product containing glibenclamide and metformin (medicinal product)
(Atom ID: 10306864)
Patient Education
Glyburide and Metformin
The combination of glyburide and metformin is used to treat type 2 diabetes (condition in which the body does not use insulin normally and therefore cannot control the amount of sugar in the blood) in people whose diabetes cannot be controlled by diet and exercise alone. Glyburide belongs to a class of drugs called sulfonylureas, and metformin is in a class of drugs called biguanides. Glyburide lowers blood sugar by causing the pancreas to produce insulin (a natural substance that is needed to break down sugar in the body) and helping the body use insulin efficiently. This medication will only help lower blood sugar in people whose bodies produce insulin naturally. Metformin helps your body control the amount of glucose (sugar) in your blood. It decreases the amount of glucose you absorb from your food and the amount of glucose made by your liver. It also helps your body use its own insulin more effectively. Glyburide and metformin are not used to treat type 1 diabetes (condition in which the body does not produce insulin and therefore cannot control the amount of sugar in the blood) or diabetic ketoacidosis (a serious condition that may occur if high blood sugar is not treated).
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Diabetes Medicines
What is diabetes?
Diabetes is a disease in which your blood glucose, or blood sugar, levels are too high. Glucose comes from the foods you eat. Insulin is a hormone that helps the glucose get into your cells to give them energy. If you have type 1 diabetes, your body does not make insulin. With type 2 diabetes, the more common type, your body does not make or use insulin well. Without enough insulin, too much glucose stays in your blood.
What are the treatments for diabetes?
Treatments for diabetes depend on the type. Common treatments include a diabetic meal plan, regular physical activity, and medicines. Some less common treatments are weight loss surgery for either type and an artificial pancreas or pancreatic islet transplantation for some people with type 1 diabetes.
Who needs diabetes medicines?
People with type 1 diabetes need to take insulin to control their blood sugar.
Some people with type 2 diabetes can control their blood sugar with healthy food choices and physical activity. But for others, a diabetic meal plan and physical activity are not enough. They need to take diabetes medicines.
The kind of medicine you take depends on your type of diabetes, daily schedule, medicine costs, and other health conditions.
What are the types of medicines for type 1 diabetes?
If you have type 1 diabetes, you must take insulin because your body no longer makes it. Different types of insulin start to work at different speeds, and the effects of each last a different length of time. You may need to use more than one type.
You can take insulin several different ways. The most common are with a needle and syringe, an insulin pen, or an insulin pump. If you use a needle and syringe or a pen, you have to take insulin several times during the day, including with meals. An insulin pump gives you small, steady doses throughout the day. Less common ways to take insulin include Inhalers, injection ports, and jet injectors.
In rare cases, taking insulin alone might not be enough to manage your blood sugar. Then you would need to take another diabetes medicine.
What are the types of medicines for type 2 diabetes?
There are several different medicines for type 2 diabetes. Each works in a different way. Many diabetes medicines are pills. There are also medicines that you inject under your skin, such as insulin.
Over time, you may need more than one diabetes medicine to manage your blood sugar. You might add another diabetes medicine or switch to a combination medicine. A combination medicine is a pill than contains more than one type of diabetes medicine. Some people with type 2 diabetes take both pills and insulin.
Even if you don't usually take insulin, you may need it at special times, such as during pregnancy or if you are in the hospital.
What else should I know about taking medicines for diabetes?
Even if you take medicines for diabetes, you still need to eat a healthy diet and do regular physical activity. These will help you manage your diabetes.
It is important to make sure that you understand your diabetes treatment plan. Talk to your provider about
- What your target blood sugar level is
- What to do if your blood sugar gets too low or too high
- Whether your diabetes medicines will affect other medicines you take
- Any side effects you have from the diabetes medicines
You should not change or stop your diabetes medicines on your own. Talk to your provider first.
Some people who take diabetes medicines may need medicines for high blood pressure, high cholesterol, or other conditions. This may help you avoid or control any complications of diabetes.
NIH: National Institute of Diabetes and Digestive and Kidney Diseases
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