Leucovorin 10 mg/ML
RxNorm 323957

Concept Hierarchy & Relationship Mapping

RxNorm Concept Unique Identifier (RxCUI) 323957 represents a standardized clinical drug concept used for cross-system interoperability. This concept aggregates multiple Atom IDs (AUIs), which are specific naming variations and synonyms used across pharmaceutical databases to ensure accurate medication mapping for: leucovorin 10 mg/ML.

The following semantic concepts and normalized strings are associated with this clinical entity:

SCDC
Leucovorin 10 mg/ML
AUI:12281130
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This clinical crossover tool is designed for healthcare professionals, pharmacists, and data analysts to safely compare substitute products and manage medication interoperability.

SCDCPrescribable

Semantic Clinical Drug Component (SCDC):
Leucovorin 10 mg/ML
(Atom ID: 12281130)

Clinical Status & Identity

Prescribable Status
YES (Active)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
leucovorin 10 MG/ML
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
323957
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12281130
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SCDC
Semantic Clinical Drug Component (Ingredient + Strength)
Source Code
323957
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

Technical Attributes & Logic

RXN BOSS STRENGTH DENOM UNIT
ML
RXN Boss Strength Denom Unit
RXN BOSS STRENGTH DENOM VALUE
1
RXN Boss Strength Denom Value
RXN BOSS STRENGTH NUM UNIT
MG
RXN Boss Strength Num Unit
RXN BOSS STRENGTH NUM VALUE
10
RXN Boss Strength Num Value
RXN STRENGTH
10 MG/ML
Strength plus unit of SCDC

Patient Education

Leucovorin


Leucovorin is used to prevent harmful effects of methotrexate (Rheumatrex, Trexall; cancer chemotherapy medication) when methotrexate is used to treat certain types of cancer. Leucovorin is also used to treat people who have accidentally received an overdose of methotrexate or similar medications. Leucovorin is in a class of medications called folic acid analogs. It works by protecting healthy cells from the effects of methotrexate or similar medications while allowing methotrexate to enter and kill cancer cells.
[Learn More]


Leucovorin Injection


Leucovorin injection is used to prevent harmful effects of methotrexate (Rheumatrex, Trexall; cancer chemotherapy medication) when methotrexate is used to to treat certain types of cancer. Leucovorin injection is used to treat people who have accidentally received an overdose of methotrexate or similar medications. Leucovorin injection is also used to treat anemia (low level of red blood cells) caused by low levels of folic acid in the body. Leucovorin injection is also used with 5-fluorouracil (a chemotherapy medication) to treat colorectal cancer (cancer that begins in the large intestine). Leucovorin injection is in a class of medications called folic acid analogs. It treats people who are receiving methotrexate by protecting healthy cells from the effects of methotrexate. It treats anemia by supplying folic acid that is needed for red blood cell formation. It treats colorectal cancer by increasing the effects of 5-fluorouracil.
[Learn More]


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