Cascara sagrada 450 mg
RxNorm 330301

Concept Hierarchy & Relationship Mapping

RxNorm Concept Unique Identifier (RxCUI) 330301 represents a standardized clinical drug concept used for cross-system interoperability. This concept aggregates multiple Atom IDs (AUIs), which are specific naming variations and synonyms used across pharmaceutical databases to ensure accurate medication mapping for: cascara sagrada 450 mg.

The following semantic concepts and normalized strings are associated with this clinical entity:

SCDC
Cascara sagrada 450 mg
AUI:12278541

This clinical crossover tool is designed for healthcare professionals, pharmacists, and data analysts to safely compare substitute products and manage medication interoperability.

SCDC

Semantic Clinical Drug Component (SCDC):
Cascara sagrada 450 mg
(Atom ID: 12278541)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
cascara sagrada 450 MG
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
N
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
330301
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12278541
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SCDC
Semantic Clinical Drug Component (Ingredient + Strength)
Source Code
330301
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

Technical Attributes & Logic

RXN BOSS STRENGTH DENOM UNIT
1
RXN Boss Strength Denom Unit
RXN BOSS STRENGTH DENOM VALUE
1
RXN Boss Strength Denom Value
RXN BOSS STRENGTH NUM UNIT
MG
RXN Boss Strength Num Unit
RXN BOSS STRENGTH NUM VALUE
450
RXN Boss Strength Num Value
RXN STRENGTH
450 MG
Strength plus unit of SCDC

Patient Education

Cascara Sagrada


What is it? Cascara sagrada is a shrub. The dried bark is used to make medicine.

Cascara sagrada used to be approved by the U.S. Food and Drug Administration (FDA) as an over-the-counter (OTC) drug for constipation. However, over the years, concerns were raised about cascara sagrada's safety and effectiveness. The FDA gave manufacturers the chance to submit safety and effectiveness information to answer these concerns. But the companies decided the cost of conducting safety and effectiveness studies would likely be more than the profit they could expect from sales of cascara sagrada. So they didn't comply with the request. As a result, the FDA notified manufacturers to remove or reformulate all OTC laxative products containing cascara sagrada from the U.S. market by November 5, 2002. Today, you can buy cascara sagrada as a "dietary supplement", but not as a drug. "Dietary supplements" don't have to meet the standards that the FDA applies to OTC or prescription drugs.

Cascara sagrada is commonly used by mouth as a laxative for constipation.

In foods and beverages, a bitterless extract of cascara sagrada is sometimes used as a flavoring agent.

In manufacturing, cascara sagrada is used in the processing of some sunscreens.


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