HYDROcodone bitartrate 3.75 mg / guaiFENesin 50 mg / pseudoephedrine HCl 22.5 mg in 5 mL Oral Solution
RxNorm 860579

Concept Hierarchy & Relationship Mapping

RxNorm Concept Unique Identifier (RxCUI) 860579 represents a standardized clinical drug concept used for cross-system interoperability. This concept aggregates multiple Atom IDs (AUIs), which are specific naming variations and synonyms used across pharmaceutical databases to ensure accurate medication mapping for: HYDROcodone bitartrate 3.75 mg / guaiFENesin 50 mg / pseudoephedrine HCl 22.5 mg in 5 mL Oral Solution.

The following semantic concepts and normalized strings are associated with this clinical entity:

SCD
Guaifenesin 10 mg/ML / hydrocodone bitartrate 0.75 mg/ML / pseudoephedrine hydrochloride 4.5 mg/ML Oral Solution
Primary clinical definition
AUI:12350955
View
TMSY
GuaiFENesin 10 mg/ML / HYDROcodone bitartrate 0.75 mg/ML / pseudoephedrine hydrochloride 4.5 mg/ML Oral Solution
AUI:12384683
View
SY
Guaifenesin 50 mg / hydrocodone bitartrate 3.75 mg / pseudoephedrine HCl 22.5 mg per 5 mL Oral Solution
AUI:11813607
View
TMSY
GuaiFENesin 50 mg / HYDROcodone bitartrate 3.75 mg / pseudoephedrine HCl 22.5 mg per 5 mL Oral Solution
AUI:11814385
View
PSN
HYDROcodone bitartrate 3.75 mg / guaiFENesin 50 mg / pseudoephedrine HCl 22.5 mg in 5 mL Oral Solution
AUI:13050182
View

This clinical crossover tool is designed for healthcare professionals, pharmacists, and data analysts to safely compare substitute products and manage medication interoperability.

SCD

Semantic Clinical Drug (SCD):
Guaifenesin 10 mg/ML / hydrocodone bitartrate 0.75 mg/ML / pseudoephedrine hydrochloride 4.5 mg/ML Oral Solution
(Atom ID: 12350955)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
guaifenesin 10 MG/ML / hydrocodone bitartrate 0.75 MG/ML / pseudoephedrine hydrochloride 4.5 MG/ML Oral Solution
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
860579
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12350955
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SCD
Semantic Clinical Drug (Ingredient + Strength + Dose Form)
Source Code
860579
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

Technical Attributes & Logic

RXN AI
{316006} 5032
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AI
{997174} 91168
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AM
{316006} 5032
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN AM
{997174} 91168
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{316006} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{997174} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN OBSOLETED
12/29/2021
Date the RxNorm atom became obsolete
RXTERM FORM
Sol
The RxTerm dose form name for this drug
TMSY

Tall Man Lettering Synonym (TMSY):
GuaiFENesin 10 mg/ML / HYDROcodone bitartrate 0.75 mg/ML / pseudoephedrine hydrochloride 4.5 mg/ML Oral Solution
(Atom ID: 12384683)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
guaiFENesin 10 MG/ML / HYDROcodone bitartrate 0.75 MG/ML / pseudoephedrine hydrochloride 4.5 MG/ML Oral Solution
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
860579
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12384683
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
TMSY
Tall Man Lettering Synonym (Tall Man Lettering synonym of another TTY, given to distinguish between commonly confused drugs.)
Source Code
860579
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
SY

Synonym (SY):
Guaifenesin 50 mg / hydrocodone bitartrate 3.75 mg / pseudoephedrine HCl 22.5 mg per 5 mL Oral Solution
(Atom ID: 11813607)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
guaifenesin 50 MG / hydrocodone bitartrate 3.75 MG / pseudoephedrine HCl 22.5 MG per 5 ML Oral Solution
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
860579
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
11813607
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SY
Synonym (Synonym of another TTY, given for clarity.)
Source Code
860579
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
TMSY

Tall Man Lettering Synonym (TMSY):
GuaiFENesin 50 mg / HYDROcodone bitartrate 3.75 mg / pseudoephedrine HCl 22.5 mg per 5 mL Oral Solution
(Atom ID: 11814385)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
guaiFENesin 50 MG / HYDROcodone bitartrate 3.75 MG / pseudoephedrine HCl 22.5 MG per 5 ML Oral Solution
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
860579
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
11814385
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
TMSY
Tall Man Lettering Synonym (Tall Man Lettering synonym of another TTY, given to distinguish between commonly confused drugs.)
Source Code
860579
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
PSN

Prescribable Name (PSN):
HYDROcodone bitartrate 3.75 mg / guaiFENesin 50 mg / pseudoephedrine HCl 22.5 mg in 5 mL Oral Solution
(Atom ID: 13050182)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
HYDROcodone bitartrate 3.75 MG / guaiFENesin 50 MG / pseudoephedrine HCl 22.5 MG in 5 mL Oral Solution
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
860579
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
13050182
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
PSN
Prescribable Name (Synonym of another TTY, given for clarity and for display purposes in electronic prescribing applications. Only one PSN per concept.)
Source Code
860579
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

Patient Education

Guaifenesin


Guaifenesin is used to relieve chest congestion. Guaifenesin may help control symptoms but does not treat the cause of symptoms or speed recovery. Guaifenesin is in a class of medications called expectorants. It works by thinning the mucus in the air passages to make it easier to cough up the mucus and clear the airways.
[Learn More]


Hydrocodone Combination Products


Hydrocodone is available in combination with other ingredients, and different combination products are prescribed for different uses. Some hydrocodone combination products are used to relieve moderate-to-severe pain. Other hydrocodone combination products are used to relieve cough. Hydrocodone is in a class of medications called opiate (narcotic) analgesics and in a class of medications called antitussives. Hydrocodone relieves pain by changing the way the brain and nervous system respond to pain. Hydrocodone relieves cough by decreasing activity in the part of the brain that causes coughing. You will take hydrocodone in combination with at least one other medication, but this monograph only provides information about hydrocodone. Be sure to read information about the other ingredients in the hydrocodone product you are taking. Ask your doctor or pharmacist if you have any questions.
[Learn More]


Pseudoephedrine


Pseudoephedrine is used to relieve nasal congestion caused by colds, allergies, and hay fever. It is also used to temporarily relieve sinus congestion and pressure. Pseudoephedrine will relieve symptoms but will not treat the cause of the symptoms or speed recovery. Pseudoephedrine is in a class of medications called nasal decongestants. It works by causing narrowing of the blood vessels in the nasal passages.
[Learn More]


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