Concept Hierarchy & Relationship Mapping
RxNorm Concept Unique Identifier (RxCUI) 866353 represents a standardized clinical drug concept used for cross-system interoperability. This concept aggregates multiple Atom IDs (AUIs), which are specific naming variations and synonyms used across pharmaceutical databases to ensure accurate medication mapping for: ZyrTEC Itchy Eye 0.025 % Ophthalmic Solution.
The following semantic concepts and normalized strings are associated with this clinical entity:
Type (TTY)
Clinical Name / Synonym
Atom ID
Details
This clinical crossover tool is designed for healthcare professionals, pharmacists, and data analysts to safely compare substitute products and manage medication interoperability.
SBD
Semantic Branded Drug (SBD):
Ketotifen 0.25 mg/ML Ophthalmic Solution [Zyrtec Itchy Eye]
(Atom ID: 12357205)
Clinical Status & Identity
Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
ketotifen 0.25 MG/ML Ophthalmic Solution [Zyrtec Itchy Eye]
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.
Interoperability & Coding
Concept ID (RxCUI)
866353
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12357205
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SBD
Semantic Branded Drug (Ingredient + Strength + Dose Form + Brand Name)
Source Code
866353
The "Most useful" identifier asserted by the original source vocabulary.
Source & Registry Data
Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
Technical Attributes & Logic
RXN AI
{330367} 11404
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AM
{330367} 6146
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{330367} AM
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN OBSOLETED
09/30/2020
Date the RxNorm atom became obsolete
RXTERM FORM
Sol
The RxTerm dose form name for this drug
TMSY
Tall Man Lettering Synonym (TMSY):
Ketotifen 0.25 mg/ML Ophthalmic Solution [ZyrTEC Itchy Eye]
(Atom ID: 12379482)
Clinical Status & Identity
Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
ketotifen 0.25 MG/ML Ophthalmic Solution [ZyrTEC Itchy Eye]
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.
Interoperability & Coding
Concept ID (RxCUI)
866353
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12379482
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
TMSY
Tall Man Lettering Synonym (Tall Man Lettering synonym of another TTY, given to distinguish between commonly confused drugs.)
Source Code
866353
The "Most useful" identifier asserted by the original source vocabulary.
Source & Registry Data
Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
SY
Synonym (SY):
Zyrtec Itchy Eye 0.025 % (ketotifen fumarate 0.035 % ) Ophthalmic Solution
(Atom ID: 3065696)
Clinical Status & Identity
Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
Zyrtec Itchy Eye 0.025 % (ketotifen fumarate 0.035 % ) Ophthalmic Solution
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.
Interoperability & Coding
Concept ID (RxCUI)
866353
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
3065696
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SY
Synonym (Synonym of another TTY, given for clarity.)
Source Code
866353
The "Most useful" identifier asserted by the original source vocabulary.
Source & Registry Data
Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
TMSY
Tall Man Lettering Synonym (TMSY):
ZyrTEC Itchy Eye 0.025 % (ketotifen fumarate 0.035 % ) Ophthalmic Solution
(Atom ID: 3730518)
Clinical Status & Identity
Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
ZyrTEC Itchy Eye 0.025 % (ketotifen fumarate 0.035 % ) Ophthalmic Solution
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.
Interoperability & Coding
Concept ID (RxCUI)
866353
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
3730518
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
TMSY
Tall Man Lettering Synonym (Tall Man Lettering synonym of another TTY, given to distinguish between commonly confused drugs.)
Source Code
866353
The "Most useful" identifier asserted by the original source vocabulary.
Source & Registry Data
Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
PSN
Prescribable Name (PSN):
ZyrTEC Itchy Eye 0.025 % Ophthalmic Solution
(Atom ID: 6401263)
Clinical Status & Identity
Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
ZyrTEC Itchy Eye 0.025 % Ophthalmic Solution
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.
Interoperability & Coding
Concept ID (RxCUI)
866353
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
6401263
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
PSN
Prescribable Name (Synonym of another TTY, given for clarity and for display purposes in electronic prescribing applications. Only one PSN per concept.)
Source Code
866353
The "Most useful" identifier asserted by the original source vocabulary.
Source & Registry Data
Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
SY
Synonym (SY):
Zyrtec Itchy Eye 0.025 % Ophthalmic Solution
(Atom ID: 2997500)
Clinical Status & Identity
Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
Zyrtec Itchy Eye 0.025 % Ophthalmic Solution
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.
Interoperability & Coding
Concept ID (RxCUI)
866353
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
2997500
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SY
Synonym (Synonym of another TTY, given for clarity.)
Source Code
866353
The "Most useful" identifier asserted by the original source vocabulary.
Source & Registry Data
Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
TMSY
Tall Man Lettering Synonym (TMSY):
ZyrTEC Itchy Eye 0.025 % Ophthalmic Solution
(Atom ID: 3726511)
Clinical Status & Identity
Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
ZyrTEC Itchy Eye 0.025 % Ophthalmic Solution
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.
Interoperability & Coding
Concept ID (RxCUI)
866353
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
3726511
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
TMSY
Tall Man Lettering Synonym (Tall Man Lettering synonym of another TTY, given to distinguish between commonly confused drugs.)
Source Code
866353
The "Most useful" identifier asserted by the original source vocabulary.
Source & Registry Data
Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
SY
Synonym (SY):
Zyrtec Itchy Eye 0.25 mg/ML Ophthalmic Solution
(Atom ID: 2997499)
Clinical Status & Identity
Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
Zyrtec Itchy Eye 0.25 MG/ML Ophthalmic Solution
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.
Interoperability & Coding
Concept ID (RxCUI)
866353
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
2997499
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SY
Synonym (Synonym of another TTY, given for clarity.)
Source Code
866353
The "Most useful" identifier asserted by the original source vocabulary.
Source & Registry Data
Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
TMSY
Tall Man Lettering Synonym (TMSY):
ZyrTEC Itchy Eye 0.25 mg/ML Ophthalmic Solution
(Atom ID: 3736785)
Clinical Status & Identity
Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
ZyrTEC Itchy Eye 0.25 MG/ML Ophthalmic Solution
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.
Interoperability & Coding
Concept ID (RxCUI)
866353
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
3736785
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
TMSY
Tall Man Lettering Synonym (Tall Man Lettering synonym of another TTY, given to distinguish between commonly confused drugs.)
Source Code
866353
The "Most useful" identifier asserted by the original source vocabulary.
Source & Registry Data
Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
