Acetaminophen 325 mg / caffeine 50 mg / phenyltoloxamine citrate 20 mg / salicylamide 250 mg Oral Capsule [Combiflex]
RxNorm 998709

Concept Hierarchy & Relationship Mapping

RxNorm Concept Unique Identifier (RxCUI) 998709 represents a standardized clinical drug concept used for cross-system interoperability. This concept aggregates multiple Atom IDs (AUIs), which are specific naming variations and synonyms used across pharmaceutical databases to ensure accurate medication mapping for: acetaminophen 325 mg / caffeine 50 mg / phenyltoloxamine citrate 20 mg / salicylamide 250 mg Oral Capsule [Combiflex].

The following semantic concepts and normalized strings are associated with this clinical entity:

SBD
Acetaminophen 325 mg / caffeine 50 mg / phenyltoloxamine citrate 20 mg / salicylamide 250 mg Oral Capsule [Combiflex]
AUI:12357201
View
SY
APAP 325 mg / Caffeine 50 mg / Phenyltoloxamine citrate 20 mg / salicylamide 250 mg Oral Capsule [Combiflex]
AUI:3857018
View
SY
Combiflex (acetaminophen 325 mg / caffeine 50 mg / phenyltoloxamine citrate 20 mg / salicylamide 250 mg) Oral Capsule
AUI:3278555
View
SY
Combiflex (APAP 325 mg / caffeine 50 mg / phenyltoloxamine citrate 20 mg / salicylamide 250 mg) Oral Capsule
AUI:3305998
View

This clinical crossover tool is designed for healthcare professionals, pharmacists, and data analysts to safely compare substitute products and manage medication interoperability.

SBD

Semantic Branded Drug (SBD):
Acetaminophen 325 mg / caffeine 50 mg / phenyltoloxamine citrate 20 mg / salicylamide 250 mg Oral Capsule [Combiflex]
(Atom ID: 12357201)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
acetaminophen 325 MG / caffeine 50 MG / phenyltoloxamine citrate 20 MG / salicylamide 250 MG Oral Capsule [Combiflex]
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
998709
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
12357201
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SBD
Semantic Branded Drug (Ingredient + Strength + Dose Form + Brand Name)
Source Code
998709
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.

Technical Attributes & Logic

RXN AI
{315263} 161
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AI
{316651} 9518
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AI
{330900} 1886
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AI
{880325} 221141
RXCUI of BOSS Active Ingredient preceded by RXCUI of SCDC responsible for value
RXN AM
{315263} 161
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN AM
{316651} 9518
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN AM
{330900} 1886
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN AM
{880325} 33408
RXCUI of BOSS Active Moiety preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{315263} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{316651} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{330900} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN BOSS FROM
{880325} AI
Source of BOSS as either from the active ingredient (AI) or the active moiety (AM) preceded by RXCUI of SCDC responsible for value
RXN OBSOLETED
04/30/2020
Date the RxNorm atom became obsolete
RXTERM FORM
Cap
The RxTerm dose form name for this drug
SY

Synonym (SY):
APAP 325 mg / Caffeine 50 mg / Phenyltoloxamine citrate 20 mg / salicylamide 250 mg Oral Capsule [Combiflex]
(Atom ID: 3857018)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
APAP 325 MG / Caffeine 50 MG / Phenyltoloxamine citrate 20 MG / salicylamide 250 MG Oral Capsule [Combiflex]
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
998709
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
3857018
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SY
Synonym (Synonym of another TTY, given for clarity.)
Source Code
998709
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
SY

Synonym (SY):
Combiflex (acetaminophen 325 mg / caffeine 50 mg / phenyltoloxamine citrate 20 mg / salicylamide 250 mg) Oral Capsule
(Atom ID: 3278555)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
Combiflex (acetaminophen 325 MG / caffeine 50 MG / phenyltoloxamine citrate 20 MG / salicylamide 250 MG) Oral Capsule
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
998709
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
3278555
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SY
Synonym (Synonym of another TTY, given for clarity.)
Source Code
998709
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.
SY

Synonym (SY):
Combiflex (APAP 325 mg / caffeine 50 mg / phenyltoloxamine citrate 20 mg / salicylamide 250 mg) Oral Capsule
(Atom ID: 3305998)

Clinical Status & Identity

Prescribable Status
NO (Reference)
Part of the RxNorm Current Prescribable Content subset including all drugs available for prescription in the USA.
Concept Description
Combiflex (APAP 325 MG / caffeine 50 MG / phenyltoloxamine citrate 20 MG / salicylamide 250 MG) Oral Capsule
Official description of the drug concept as defined in the source vocabulary.
Suppress Flag
O
N: Not suppressible | O: Obsolete | Y: Suppressed by editor | E: Unquantified non-prescribable drug.

Interoperability & Coding

Concept ID (RxCUI)
998709
RxNorm Unique Identifier for the standardized concept.
Atom ID (RXAUI)
3305998
Unique identifier for this specific name variation (Atom).
Term Type (TTY)
SY
Synonym (Synonym of another TTY, given for clarity.)
Source Code
998709
The "Most useful" identifier asserted by the original source vocabulary.

Source & Registry Data

Source Name
RxNorm Vocabulary (RXNORM)
The official name and abbreviation for the vocabulary source.
Source Version
20AA_260601F
The specific version of the vocabulary provided by the source.
Update Date
June 01, 2026
The date when this RxNorm data was last updated by the NLM.
License Contact
RxNorm Customer Service, , U.S. National Library of Medicine, 8600 Rockville Pike, , Bethesda, MD, United States, 20894, (888) FIND-NLM, , https://support.nlm.nih.gov/support/create-case/, https://www.nlm.nih.gov/research/umls/rxnorm/
Source licensing contact information.