EFRANARELAXIN ALFA
UNII 03X92LE3ZC

Substance Identification & Data

This profile provides standardized clinical and technical data for Efranarelaxin Alfa, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 03X92LE3ZC.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2969217-22-7 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
03X92LE3ZC
CAS Registry Number
2969217-22-7
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
EFRANARELAXIN ALFA
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
C220989
National Cancer Institute reference terminology for clinical and research data.
INN ID
13420
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
Efranarelaxin alfa
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Efranarelaxin Alfa. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

Efranarelaxin alfa

Common Names & Synonyms

Immunoglobulin G1 [14-phenylalanine,15-glutamic acid,111-serine,134-cysteine,146-tryptophan,de-C-terminal lysine], (human γ1-chain C-region C-terminal fragment) fusion protein with peptide linker ((GGGGS)3GGGGGS) fusion protein with relaxin H2 A-chain (human), (6→6′),(9→9′),(134→129′),(258→257′),(271→269′)-pentakis(disulfide) with immunoglobulin G1 [14′-phenylalanine,15′-glutamic acid,111′-serine,129′-cysteine,146′-serine,148′-alanine,187′-valine,de-C-terminal lysine] (human γ1-chain C-region C-terminal fragment) fusion protein with peptide linker ((GGGGS)3GGGGGS) fusion protein with 2-29-relaxin H2 B-chain (human)
efranarelaxin alfa [INN]
human immunoglobulin G1 (IgG1) Fc fragment (h-CH2-CH3-CHS domains) (1-226) [Homo sapiens IGHG1*03 (hinge (1-10), CH2 L<sup>14</sup>>F, L<sup>15</sup>>E, P<sup>111</sup>>S (11-120), CH3 S<sup>134</sup>>C, T<sup>146</sup>>W (121-225), CHS K227>del (226))] fused via peptide linker (G<sub>4</sub>S) <sub>3</sub>G<sub>5</sub>S (227-247) to the chain A of human relaxin H2 (RLN2) (1-24, 248-271 in the actual sequence), heterodimer (6-6':9-9':134-129':258-257':271-269')-pentakisdisulfide with human immunoglobulin G1 (IgG1) Fc fragment (h-CH2-CH3-CHS domains) (1'-226') [Homo sapiens IGHG1*03 (hinge (1'-10'), CH2 L<sup>14'</sup>>F, L<sup>15'</sup>>E, P<sup>111'</sup>>S (11'-120'), CH3 T<sup>146'</sup>>S, L<sup>148'</sup>>A, Y<sup>187'</sup>>V (121'-225'), CHS K<sup>227'</sup>>del (226'))] fused via peptide linker (G<sub>4</sub>S) <sub>3</sub>G<sub>5</sub>S (227'-247') to the des-Asp<sup>1</sup>-chain B of human relaxin H2 (RLN2) (2-29, 248'-275' in the actual sequence), produced in Chinese hamster ovary (CHO) cells, cell line CHO-K1, glycoform alfa

External Clinical & Regulatory Resources

CAS
Common Chemistry
NCATS
Inxight Drugs
NLM
DailyMed Products
NCATS
GSRS Full Record
NIH
NCI Thesaurus