TISLELIZUMAB
UNII 0KVO411B3N

Substance Identification & Data

This profile provides standardized clinical and technical data for Tislelizumab, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 0KVO411B3N.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 1858168-59-8 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

0KVO411B3N

CAS Registry Number

1858168-59-8

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

TISLELIZUMAB

Official standardized name for this substance within the FDA UNII nomenclature system.

Molecular Formula

0KVO411B3N

The specific atomic composition represented as a molecular structure string.

NCI Thesaurus

C121775

National Cancer Institute reference terminology for clinical and research data.

INN ID

10553

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

FG-151

Identifier assigned by the United States Adopted Names Council.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Tislelizumab. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

TISLELIZUMAB

TISLELIZUMAB-JSGR

Common Names & Synonyms

TISLELIZUMAB [INN]

TISLELIZUMAB [USAN]

TISLELIZUMAB [WHO-DD]

TISLELIZUMAB JSGR [WHO-DD]

Brand / Trade Names

TEVIMBRA

Systematic Nomenclature

IMMUNOGLOBULIN G4, ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1) SYNTHETIC CLONE 317-4B6 HEAVY CHAIN VH FRAGMENT FUSION PROTEIN WITH HUMAN .GAMMA.4 CHAIN CLONE MUT10 EFFECTOR/CONSTANT DOMAIN FRAGMENT, DISULFIDE WITH ANTI-(HUMAN PROGRAMMED CELL DEATH PROTEIN 1) SYNTHETIC CLONE 317-4B6 LIGHT CHAIN VL FRAGMENT FUSION PROTEIN WITH HUMAN .KAPPA. CHAIN CONSTANT REGION FRAGMENT, DIMER

SYS

IMMUNOGLOBULIN G4-KAPPA, ANTI-(HOMO SAPIENS PDCD1 (PROGRAMMED CELL DEATH 1, PD-1, PD1, CD279)), HUMANIZED MONOCLONAL ANTIBODYGAMMA4 HEAVY CHAIN (1-445) (HUMANIZED VH (HOMO SAPIENS IGHV4-59*01 (88.70%) -(IGHD) -IGHJ3*01 M123>T (113)) (8.7.12) (1-118) -HOMO SAPIENS IGHG4*01 (CH1 (119-216), HINGE S10>P (226) (217-228), CH2 E1.4>P (231), F1.3>V (232), L1.2>A (233), D27>A (263) (229-338), CH3 R88>K (407) (339-443), CHS (444-445)) (119-445)), (132-214')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'- 214') (HUMANIZED V-KAPPA (HOMO SAPIENS IGKV4-1*01 (81.20%) -IGKJ2*01) (6.3.9) (1'-107') -HOMO SAPIENS IGKC*01, KM3 A45.1 (153), V101 (191) (108'-214'))DIMER (224-224'':227-227'')-BISDISULFIDE

SYS