BINIMETINIB
UNII 181R97MR71

Substance Identification & Data

This profile provides standardized clinical and technical data for Binimetinib, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 181R97MR71.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 606143-89-9 and the RxNorm Concept ID (RxCUI) 2049122. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
181R97MR71
CAS Registry Number
606143-89-9
RxNorm Concept ID

Detailed Substance Profile

Preferred Name
BINIMETINIB
Official standardized name for this substance within the FDA UNII nomenclature system.
Molecular Formula
181R97MR71
The specific atomic composition represented as a molecular structure string.
InChIKey
C17H15BrF2N4O3
International Chemical Identifier digital signature for unique molecular identification.
SMILES String
ACWZRVQXLIRSDF-UHFFFAOYSA-N
Line notation for describing the chemical structure and connectivity of atoms.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
PubChem CID
Unique identification number in the NCBI database of chemical substances.
INN ID
9764
Sequential identifier assigned via the WHO International Nonproprietary Name program.
USAN ID
BC-93
Identifier assigned by the United States Adopted Names Council.
Substance Type
chemical
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Ingredient Role
N(c1c(C(NOCCO)=O)cc2c(c1F)ncn2C)c3c(F)cc(Br)cc3

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Binimetinib. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

BINIMETINIB

Common Names & Synonyms

BINIMETINIB [INN]
BINIMETINIB [JAN]
BINIMETINIB [MI]
BINIMETINIB [ORANGE BOOK]
BINIMETINIB [USAN]
BINIMETINIB [WHO-DD]

Brand / Trade Names

MEKTOVI

Systematic Nomenclature

1H-BENZIMIDAZOLE-6-CARBOXAMIDE, 5-((4-BROMO-2-FLUOROPHENYL)AMINO)-4-FLUORO-N-(2-HYDROXYETHOXY)-1-METHYL-
5-((4-BROMO-2-FLUOROPHENYL)AMINO)-4-FLUORO-N-(2-HYDROXYETHOXY)-1-METHYL-1H-BENZIMIDAZOLE-6-CARBOXAMIDE
6-((4-BROMO-2-FLUOROPHENYL)AMINO)-7-FLUORO-N-(2-HYDROXYETHOXY)-3-METHYLBENZIMIDAZOLE-5-CARBOXAMIDE

Technical Codes

ARRY-162
ARRY-438162
MEK162
MEK-162
NVP-MEK162

NDC Products Containing BINIMETINIB

This unique ingredient identifier is listed as an ingredient or substance in the following products in the NDC directory: