IVACAFTOR
UNII 1Y740ILL1Z

Substance Identification & Data

This profile provides standardized clinical and technical data for Ivacaftor, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 1Y740ILL1Z.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 873054-44-5 and the RxNorm Concept ID (RxCUI) 1243041. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
1Y740ILL1Z
CAS Registry Number
873054-44-5
RxNorm Concept ID

Detailed Substance Profile

Preferred Name
IVACAFTOR
Official standardized name for this substance within the FDA UNII nomenclature system.
Molecular Formula
1Y740ILL1Z
The specific atomic composition represented as a molecular structure string.
InChIKey
C24H28N2O3
International Chemical Identifier digital signature for unique molecular identification.
SMILES String
PURKAOJPTOLRMP-UHFFFAOYSA-N
Line notation for describing the chemical structure and connectivity of atoms.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
PubChem CID
Unique identification number in the NCBI database of chemical substances.
INN ID
9263
Sequential identifier assigned via the WHO International Nonproprietary Name program.
USAN ID
WW-53
Identifier assigned by the United States Adopted Names Council.
Substance Type
chemical
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Ingredient Role
c1ccc2[nH]cc(c(c2c1)=O)C(=O)Nc3c(cc(c(c3)O)C(C)(C)C)C(C)(C)C

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Ivacaftor. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

IVACAFTOR

Common Names & Synonyms

IVACAFTOR [INN]
IVACAFTOR [MI]
IVACAFTOR [orange book]
IVACAFTOR [USAN]
IVACAFTOR [VANDF]
IVACAFTOR [WHO-DD]

Brand / Trade Names

KALYDECO
ORKAMBI COMPONENT IVACAFTOR
SYMKEVI COMPONENT IVACAFTOR
TRIKAFTA COMPONENT IVACAFTOR

Systematic Nomenclature

3-QUINOLINECARBOXAMIDE, N-(2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL)-1,4-DIHYDRO-4-OXO-
N-(2,4-BIS(1,1-DIMETHYLETHYL)-5-HYDROXYPHENYL)-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXAMIDE
N-(2,4-DI-TERT-BUTYL-5-HYDROXYPHENYL)-4-OXO-1,4-DIHYDROQUINOLINE-3-CARBOXAMIDE

Technical Codes

VX-770

NDC Products Containing IVACAFTOR

This unique ingredient identifier is listed as an ingredient or substance in the following products in the NDC directory: