AVALOTCAGENE ONTAPARVOVEC
UNII 20E4R0BF12

Substance Identification & Data

This profile provides standardized clinical and technical data for Avalotcagene Ontaparvovec, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 20E4R0BF12.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2227000-30-6 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

20E4R0BF12

CAS Registry Number

2227000-30-6

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

AVALOTCAGENE ONTAPARVOVEC

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C171792

National Cancer Institute reference terminology for clinical and research data.

INN ID

11153

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

HI-242

Identifier assigned by the United States Adopted Names Council.

Substance Type

structurallyDiverse

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Avalotcagene Ontaparvovec. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

AVALOTCAGENE ONTAPARVOVEC

Common Names & Synonyms

A RECOMBINANT NON-REPLICATING ADENO-ASSOCIATED VIRUS TYPE 2/8 (RAAV REP2-CAP8) VECTOR, ENCODING CODON-OPTIMIZED, WILD-TYPE HUMAN ORNITHINE TRANSCARBAMYLASE (OTC) UNDER THE CONTROL OF A HYBRID HUMAN THYROXINE-BINDING GLOBULIN (TBG) / HUMAN ALPHA 1-MICROGLOBULIN/BIKUNIN PRECURSOR (AMBP) PROMOTER/ENHANCER. THE VECTOR GENOME IS A HEAD-TO-HEAD DIMER, WITH THE VECTOR GENOME CASSETTE LOCATED 5' OF THE MUTATED INTERNAL INVERTED TERMINAL REPEAT (ITR) IN A REVERSE ORIENTATION AND THE VECTOR GENOME CASSETTE LOCATED 3' OF THE MUTATED INTERNAL ITR IN A FORWARD ORIENTATION

AVALOTCAGENE ONTAPARVOVEC [INN]

AVALOTCAGENE ONTAPARVOVEC [USAN]

DTX-301 (ORNITHINE-TRANSCARBAMYLASE-GENE-THERAPY)

SCAAV8OTC