SOTORASIB
UNII 2B2VM6UC8G

Substance Identification & Data

This profile provides standardized clinical and technical data for Sotorasib, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 2B2VM6UC8G.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2296729-00-3 and the RxNorm Concept ID (RxCUI) 2550714. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

2B2VM6UC8G

CAS Registry Number

2296729-00-3

RxNorm Concept ID

2550714

Detailed Substance Profile

Preferred Name

SOTORASIB

Official standardized name for this substance within the FDA UNII nomenclature system.

Molecular Formula

2B2VM6UC8G

The specific atomic composition represented as a molecular structure string.

InChIKey

C30H30F2N6O3

International Chemical Identifier digital signature for unique molecular identification.

SMILES String

NXQKSXLFSAEQCZ-SFHVURJKSA-N

Line notation for describing the chemical structure and connectivity of atoms.

NCI Thesaurus

C154287

National Cancer Institute reference terminology for clinical and research data.

PubChem CID

137278711

Unique identification number in the NCBI database of chemical substances.

INN ID

11370

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

HI-164

Identifier assigned by the United States Adopted Names Council.

Substance Type

chemical

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Ingredient Role

c1c(c(nc2c1c(nc(n2-c3c(ccnc3C(C)C)C)=O)N4[C@H](CN(CC4)C(C=C)=O)C)-c5c(cccc5O)F)F

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Sotorasib. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

SOTORASIB

Common Names & Synonyms

KRAS G12C INHIBITOR 9

KRAS MUTANT-TARGETING AMG 510

SOTORASIB [INN]

SOTORASIB [JAN]

SOTORASIB [ORANGE BOOK]

SOTORASIB [USAN]

SOTORASIB [WHO-DD]

Brand / Trade Names

LUMAKRAS

Systematic Nomenclature

(1M)-6-FLUORO-7-(2-FLUORO-6-HYDROXYPHENYL)-1-(4-METHYL-2-(PROPAN-2-YL)PYRIDIN-3-YL)-4-((2S)-2-METHYL-4-(PROP-2-ENOYL)PIPERAZIN-1-YL)PYRIDO(2,3-D)PYRIMIDIN-2(1H)-ONE

SYS

(1RA)-6-FLUORO-7-(2-FLUORO-6-HYDROXYPHENYL)-4-((2S)-2-METHYL-4-(1-OXOPROP-2-EN-1-YL)PIPERAZIN-1-YL)-1-(4-METHYL-2-(PROPAN-2-YL)PYRIDIN-3-YL)PYRIDO(2,3-D)PYRIMIDIN-2(1H)-ONE

SYS

6-FLUORO-7-(2-FLUORO-6-HYDROXYPHENYL)-(1M)-1-(4-METHYL-2-(PROPAN-2-YL)PYRIDIN-3-YL)-4-((2S)-2-METHYL-4-(PROP-2-ENOYL)PIPERAZIN-1-YL)PYRIDO(2,3-D)PYRIMIDIN-2(1H)-ONE

SYS

PYRIDO(2,3-D)PYRIMIDIN-2(1H)-ONE, 6-FLUORO-7-(2-FLUORO-6-HYDROXYPHENYL)-1-(4-METHYL-2-(1-METHYLETHYL)-3-PYRIDINYL)-4-((2S)-2-METHYL-4-(1-OXO-2-PROPEN-1-YL)-1-PIPERAZINYL)-

SYS

PYRIDO(2,3-D)PYRIMIDIN-2(1H)-ONE, 6-FLUORO-7-(2-FLUORO-6-HYDROXYPHENYL)-1-(4-METHYL-2-(1-METHYLETHYL)-3-PYRIDINYL)-4-((2S)-2-METHYL-4-(1-OXO-2-PROPEN-1-YL)-1-PIPERAZINYL)-, (1R)-

SYS