EFTEZIRLEUKIN ALFA
UNII 2JT3AAX4HJ

Substance Identification & Data

This profile provides standardized clinical and technical data for Eftezirleukin Alfa, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 2JT3AAX4HJ.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 3055295-61-6 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

2JT3AAX4HJ

CAS Registry Number

3055295-61-6

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

EFTEZIRLEUKIN ALFA

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C226347

National Cancer Institute reference terminology for clinical and research data.

INN ID

13936

Sequential identifier assigned via the WHO International Nonproprietary Name program.

Substance Type

Eftezirleukin Alfa

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Eftezirleukin Alfa. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

Eftezirleukin Alfa

Common Names & Synonyms

Immunoglobulin G4 [10-proline,16-alanine,17-alanine,148-tryptophan,de-229-lysine] (human γ4-chain hinge-CH2-CH3 fragment) fusion protein with peptide linker (GGGGGS)4 fusion protein with 6-133-interleukin 2 [38-glycine,42-alanine,62-alanine,125-serine] (human), disulfide with immunoglobulin G4 [10-proline,16-alanine,17-alanine,148-serine,150-alanine,189-valine,217-arginine,218-phenylalanine] (human γ4-chain hinge-CH2-CH3 fragment)

eftezirleukin alfa [INN]

human immunoglobulin G4 (IgG4) Fc fragment (h-CH2-CH3-CHS domains) (1-228) [Homo sapiens IGHG4*01 (hinge S10>P (1-12), CH2 F16>A, L17>A (13-122), CH3 T148>W (123-227), CHS K229>del (228-228))] fused via peptide linker 229(GGGGS)4248 to human interleukin-2 (IL-2, IL2, Uniprot: P60568) fragment (6-133, 249-376 in the current sequence) variant (R38>G281 , F42> A285, E62>A305, C125>S368), (8-8':11-11')-bisdisulfide with human immunoglobulin G4(IgG4) Fc fragment (h-CH2-CH3-CHS domains) (1'-229') [Homo sapiens IGHG4*01 (hinge S 10' >P (1'-12'), CH2 F16' >A, 17' >A (13'-122'), CH3 T148' >S, L150' >A, Y 189' >V, H217' >R, Y218' >F (123'-227'), CHS (228'-229'))], produced in Chinese hamster ovary (CHO) cells, cell line CHO-ZN, glycoform alfa

External Clinical & Regulatory Resources

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