FAMZERETCEL
UNII 2QX977G5YV

Substance Identification & Data

This profile provides standardized clinical and technical data for Famzeretcel, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 2QX977G5YV.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number N/A and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

2QX977G5YV

CAS Registry Number

N/A

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

FAMZERETCEL

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C190367

National Cancer Institute reference terminology for clinical and research data.

INN ID

12260

Sequential identifier assigned via the WHO International Nonproprietary Name program.

Substance Type

structurallyDiverse

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

ITIS TSN

180092

Taxonomic Serial Number for species identified in the Integrated Taxonomic Information System.

NCBI Taxonomy

9606

Unique numeric identifier used to specify biological species in the NCBI database.

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Famzeretcel. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

FAMZERETCEL

Common Names & Synonyms

ALLOGENEIC HUMAN RETINAL PROGENITOR CELLS (HRPCS) DERIVED FROM FOETAL RETINA (17-20 WEEKS GESTATION). THE RETINAL TISSUE UNDERGOES DISSECTION AND DIGESTION AND THE OBTAINED CELLS ARE GROWN ON FIBRONECTIN-COATED PLATES UNDER HYPOXIC CONDITIONS IN SERUM FREE HIGH NUTRIENT MEDIA. THE FINAL CELL POPULATION IS CHARACTERIZED BY THE EXPRESSION OF RETINAL SPECIFICATION GENES (NESTIN, >95%; SOX2, >85%; KI67, >50%) AND AS WELL AS BY EVIDENCE OF DIFFERENTIATION INTO NEURONS (NEURONAL MIGRATION PROTEIN DOUBLECORTIN (DCX)) AND GLIA (GLIAL FIBRILLARY ACIDIC PROTEIN (GFAP; <5%). THE CELLS SECRETE OSTEOPONTIN (OPN), AND THE SECRETED OPN TOGETHER WITH OTHER TROPHIC FACTORS CAN GIVE PROTECTION TO A HUMAN RETINOBLASTOMA (HRB) CELL LINE TREATED WITH A HISTONE DEACETYLASE INHIBITOR

FAMZERETCEL [INN]

External Clinical & Regulatory Resources

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