TIXENTAMIG
UNII 2X6WP45UD6
Substance Identification & Data
This profile provides standardized clinical and technical data for Tixentamig, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 2X6WP45UD6.
Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2969220-04-8 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.
2X6WP45UD6
2969220-04-8
N/A
Detailed Substance Profile
Preferred Name
TIXENTAMIG
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
National Cancer Institute reference terminology for clinical and research data.
INN ID
13477
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
Tixentamig
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
Synonyms and Nomenclature
This section provides a complete list of nomenclature and identifier mappings for Tixentamig. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.
FDA Official Name
Tixentamig
Common Names & Synonyms
H-gamma1 heavy chain anti-CD3E (1-455) [VH (Homo sapiens IGHV3-73*01 (92.0%) -(IGHD) -IGHJ6*01 (90.9%) T123>L (120), CDR-IMGT [8.10.16] (26-33.51-60.99-114))(1-125) -Homo sapiens IGHG1*03v, G1m3>G1m17, nG1m1 CH1 K120, CH3 E12, M14, 6-G1v14-1 CH2 A1.3, A1.2, A1, 14-G1v32 CH3 W22 (knob), 14-G1v74 CH3 C10 (CH1R120>K (222) (126-223), hinge 1-15 (224-238), CH2 L1.3>A (242), L1.2>A (243), G1>A (245) (239-348), CH3 S10>C (362), E12 (364), M14 (366), T22>W (374) (349-453), CHS (454-455)) (126-455)], (228-214')-disulfide with L-lambda2 light chain anti-CD3E (1'-215') [V-LAMBDA Musmus/Homsap (Mus musculus IGLV1*01 (81.2%) -IGLJ1*01 (100%)/Homo sapiens IGLV7-46*02 (80.0%) -IGLJ3*02 (100%), CDR-IMGT [9.3.9] (26'-34'.52'-54'.91'-99')) (1'-109') -Homo sapiens IGLC2*01 (100%) (CLAMBDA2) (110'-215')]; scFvhh-G1(h-CH2-CH3) heavy chain anti-CLDN18 (1''-491'') [VH (Homo sapiens IGHV3-74*03 (94.9%) -(IGHD) -IGHJ1*01 (90.0%) W118>R (111''), L124>T (116''), CDR-IMGT [8.8.14] (26''-33''.51''-58''.97''-110'')) (1''-121'') -15-mer tris(tetraglycylseryl) linker (122''-136'') -VH (Homo sapiens IGHV3-74*03 (94.9%) -IGHD -IGHJ1*01 (90.0%) W118>R (247''), L124>T (252''), CDR-IMGT [8.8.14] (162''-169''.187''-194''.233''-246'')) (137''-257'') -2-mer alanyl-seryl linker (258''-259'') -Homo sapiens IGHG1*03v h-CH2-CH3-CHS, G1m3>G1m17, nG1m1 CH3 E12, M14, 15-G1v37 hinge S5, 6-G1v14-1 CH2 A1.3, A1.2, A1, 14-G1v33 CH3 S22, A24, V86 (hole), 14-G1v75 CH3 C5 (hinge 1-15 C5>S (264'') (260''-274''), CH2 L1.3>A (278), L1.2>A (279), G1>A (281) (275''-384''), CH3 Y5>C (393''), E12 (400), M14 (402), T22>S (410''), L24>A (412''), Y86>V (451'') (385''-489''), CHS (490''-491'')) (260''-491'')]; dimer (234-270'':237-273'')-bisdisulfide, produced in a cell line from Chinese hamster ovary (CHO) cells, derived from the cell line CHO-K1, glycoform alfa
Immunoglobulin G1, bispecific, anti-(human claudin CLDN18.2) (human monoclonal PR007245 single-domain VH-(GGGGS)3-VH fragment) fusion protein with immunoglobulin G1 [5-serine,19-alanine,20-alanine,22-alanine,134-cysteine,151-serine,153-alanine,192-valine] (human γ-1 chain C-region C-terminal fragment), (270→234′),(273→237′),(393→362′)-tris(disulfide) with immunoglobulin G1,[242′-alanine,243′-alanine,245′-alanine,362′-cysteine,374′-tryptophan] anti-(human CD3 antigen ε-chain) (human-Mus musculus monoclonal PR003886 γ1-chain), (Cys-228′→Cys-214")-disulfide with immunoglobulin, anti-(human CD3 antigen ε-chain) (human-Mus musculus monoclonal PR003886 λ2/3-chain)
immunoglobulin (H-gamma1_L-kappa)_scFvhh-G1(h-CH2-CH3), anti-[Homo sapiens CD3E (CD3 epsilon, Leu-4)] and anti-[Homo sapiens CLDN18 (claudin 18, claudin-18, surfactant associated protein J, SFTPJ) isoform 2], monoclonal antibody, bispecific, trivalent (tixentamig)
tixentamig [INN]
