COBOMARSEN
UNII 3JKW7CI9IU

Substance Identification & Data

This profile provides standardized clinical and technical data for Cobomarsen, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 3JKW7CI9IU.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 1848257-52-2 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

3JKW7CI9IU

CAS Registry Number

1848257-52-2

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

COBOMARSEN

Official standardized name for this substance within the FDA UNII nomenclature system.

InChIKey

C148H177N52O77P13S13

International Chemical Identifier digital signature for unique molecular identification.

SMILES String

NNUHKSNTEOVPHV-XHZCTNOISA-N

Line notation for describing the chemical structure and connectivity of atoms.

NCI Thesaurus

C124225

National Cancer Institute reference terminology for clinical and research data.

PubChem CID

126480232

Unique identification number in the NCBI database of chemical substances.

INN ID

10570

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

DE-136

Identifier assigned by the United States Adopted Names Council.

Substance Type

COBOMARSEN

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Ingredient Role

S=P(OC[C@@]12O[C@H]([C@@H]([C@@H]1OP(O)(=S)OC[C@H]3O[C@H](C[C@@H]3OP(O)(=S)OC[C@@]45O[C@@H](n6c7c(nc6)c([nH]c(n7)N)=O)[C@@H]([C@@H]4OP(OC[C@H]8O[C@H](C[C@@H]8OP(O)(=S)OC[C@@]9%10O[C@H]([C@@H]([C@@H]9OP(OC[C@@]%11%12O[C@H]([C@@H]([C@@H]%11OP(O)(=S)OC[C@@]%13%14O[C@H]([C@@H]([C@@H]%13OP(O)(=S)OC[C@@]%15%16O[C@H]([C@@H]([C@@H]%15O)OC%16)n%17c%18c(nc%17)c(ncn%18)N)OC%14)n%19c([nH]c(=O)c(c%19)C)=O)OC%12)n%20c([nH]c(=O)c(c%20)C)=O)(O)=S)OC%10)n%21c%22c(nc%21)c(ncn%22)N)n%23c(nc(N)cc%23)=O)(O)=S)OC5)n%24c%25c(nc%24)c(ncn%25)N)OC2)n%26c([nH]c(=O)c(c%26)C)=O)(O)O[C@@H]%27[C@]%28(O[C@H]([C@@H]%27OC%28)n%29c([nH]c(=O)c(c%29)C)=O)COP(O)(=S)O[C@@H]%30[C@@H](COP(O)(=S)O[C@H]%31C[C@@H](O[C@@H]%31COP(O)(=S)O[C@@H]%32[C@]%33(O[C@H]([C@@H]%32OC%33)n%34c(nc(N)c(c%34)C)=O)COP(O)(=S)O[C@@H]%35[C@@H](COP(O)(=S)O[C@@H]%36[C@]%37(O[C@H]([C@@H]%36OC%37)n%38c(nc(N)c(c%38)C)=O)CO)O[C@H](C%35)n%39c%40c(nc%39)c(ncn%40)N)n%41c%42c(nc%41)c([nH]c(n%42)N)=O)O[C@H](C%30)n%43c%44c(nc%43)c(ncn%44)N

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Cobomarsen. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

COBOMARSEN

Common Names & Synonyms

COBOMARSEN [USAN]

Cobomarsen [WHO-DD]

cobomarsen [INN]

Systematic Nomenclature

1-[(1R,3R,4R,7S)-1-[[[(1R,3R,4R,7S)-1-[[[(2R,3S,5R)-2-[[[(2R,3S,5R)-2-[[[(1R,3R,4R,7S)-3-(4-amino-5-methyl-2-oxopyrimidin-1-yl)-1-[[[(2R,3S,5R)-2-[[[(1S,3R,4R,7S)-3-(4-amino-5-methyl-2-oxopyrimidin-1-yl)-1-(hydroxymethyl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl]oxy-hydroxyphosphinothioyl]oxymethyl]-5-(6-aminopurin-9-yl)oxolan-3-yl]oxy-hydroxyphosphinothioyl]oxymethyl]-2,5-dioxabicyclo[2.2.1]heptan-7-yl]oxy-hydroxyphosphinothioyl]oxymethyl]-5-(2-amino-6-oxo-1H-purin-9-yl)oxolan-3-yl]oxy-hydroxyphosphinothioyl]oxymethyl]-5-(6-aminopurin-9-yl)oxolan-3-yl]oxy-hydroxyphosphinothioyl]oxymethyl]-3-(5-methyl-2,4-dioxopyrimidin-1-yl)-2,5-dioxabicyclo[2.2.1]heptan-7-yl]oxy-hydroxyphosphinothioyl]oxymethyl]-7-[[(2R,3S,5R)-3-[[(1R,3R,4R,7S)-3-(2-amino-6-oxo-1H-purin-9-yl)-7-[[(2R,3S,5R)-5-(4-amino-2-oxopyrimidin-1-yl)-3-[[(1R,3R,4R,7S)-3-(6-aminopurin-9-yl)-7-[[(1R,3R,4R,7S)-7-[[(1R,3R,4R,7S)-7-[[(1R,3R,4R,7S)-3-(6-aminopurin-9-yl)-7-hydroxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-hydroxyphosphinothioyl]oxy-3-(5-methyl-2,4-dioxopyrimidin-1-yl)-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-hydroxyphosphinothioyl]oxy-3-(5-methyl-2,4-dioxopyrimidin-1-yl)-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-hydroxyphosphinothioyl]oxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-hydroxyphosphinothioyl]oxyoxolan-2-yl]methoxy-hydroxyphosphinothioyl]oxy-2,5-dioxabicyclo[2.2.1]heptan-1-yl]methoxy-hydroxyphosphinothioyl]oxy-5-(6-aminopurin-9-yl)oxolan-2-yl]methoxy-hydroxyphosphinothioyl]oxy-2,5-dioxabicyclo[2.2.1]heptan-3-yl]-5-methylpyrimidine-2,4-dione

SYS

ALL-P-AMBO-5-METHYL-2'-O,4'-C-METHYLENE-P-THIOCYTIDYLYL-(3'->5')-2'-DEOXY-P-THIOADENYLYL-(3'->5')-5-METHYL-2'-O,4'-CMETHYLENE-P-THIOCYTIDYLYL-(3'->5')-2'-DEOXY-P-THIOGUANYLYL-(3'->5')-2'-DEOXY-P-THIOADENYLYL-(3'->5')-5-METHYL-2'-O,4'-CMETHYLENE-P-THIOURIDYLYL-(3'->5')-5-METHYL-2'-O,4'-CMETHYLENE-P-THIOURIDYLYL-(3'->5')-2'-DEOXY-P-THIOADENYLYL-(3'->5')-2'-O,4'-C-METHYLENE-P-THIOGUANYLYL-(3'->5')-2'- DEOXY-P-THIOCYTIDYLYL-(3'->5')-2'-O,4'-C-METHYLENE-PTHIOADENYLYL-(3'->5')-5-METHYL-2'-O,4'-C-METHYLENE-PTHIOURIDYLYL-(3'->5')-5-METHYL-2'-O,4'-C-METHYLENE-PTHIOURIDYLYL-(3'->5')-2'-O,4'-C-METHYLENEADENOSINE

SYS