DARGISTOTUG
UNII 4O3LRM3I5J

Substance Identification & Data

This profile provides standardized clinical and technical data for Dargistotug, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 4O3LRM3I5J.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2649362-29-6 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

4O3LRM3I5J

CAS Registry Number

2649362-29-6

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

DARGISTOTUG

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C173891

National Cancer Institute reference terminology for clinical and research data.

INN ID

12349

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

MN-227

Identifier assigned by the United States Adopted Names Council.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Dargistotug. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

DARGISTOTUG

Common Names & Synonyms

DARGISTOTUG [INN]

DARGISTOTUG [USAN]

M 6223 [WHO-DD]

Systematic Nomenclature

IMMUNOGLOBULIN G1 (DE-C-TERMINAL-LYSINE), ANTI-(HUMAN RECEPTOR TIGIT) (HUMAN MONOCLONAL M6223 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN MONOCLONAL M6223 .KAPPA.-CHAIN, DIMER

SYS

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS TIGIT (T-CELL IMMUNORECEPTOR WITH IG DOMAIN AND ITIM, V-SET IG MEMBER 9, VSIG9, V-SET AND TRANSMEMBRANE MEMBER 3, VSTM3)), HOMO SAPIENS MONOCLONAL ANTIBODY; GAMMA1 HEAVY CHAIN HOMO SAPIENS (1-450) (VH (HOMO SAPIENS IGHV7-4-1*02 (99%) -(IGHD) -IGHJ3*01 (93.3%), CDR-IMGT (8.8.15) (26-33.51-58.97-111)) (1-122)-HOMO SAPIENS IGHG1*03, G1M3, NG1M1 (CH1 R120 (219) (123-220), HINGE 1-15 (221-235), CH2 (236-345), CH3 E12 (361), M14 (363) (346-450), CHS K2>DEL (451)) (123-451)), (225-213')-DISULFIDE WITH KAPPA LIGHT CHAIN HOMO SAPIENS (1'-213') (V-KAPPA (HOMO SAPIENS IGKV1-9*01 (98.9%)-IGKJ4*01 (100%), CDR-IMGT (6.3.8) (27-32.50-52.89-96)) (1'-106') -HOMO SAPIENS IGKC*01 (100%), KM3, A45.1 (152), V101 (190) (107'-213')); DIMER (231-231'':234-234'')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, CELL LINE CHO-K1SV, GLYCOFORM ALFA

SYS