SERSACABTAGENE AUTOLEUCEL
UNII 4PM5Q6QW35

Substance Identification & Data

This profile provides standardized clinical and technical data for Sersacabtagene Autoleucel, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 4PM5Q6QW35.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number N/A and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code
4PM5Q6QW35
CAS Registry Number
N/A
RxNorm Concept ID
N/A

Detailed Substance Profile

Preferred Name
SERSACABTAGENE AUTOLEUCEL
Official standardized name for this substance within the FDA UNII nomenclature system.
NCI Thesaurus
C216003
National Cancer Institute reference terminology for clinical and research data.
INN ID
13437
Sequential identifier assigned via the WHO International Nonproprietary Name program.
Substance Type
structurallyDiverse
ISO 11238 classification category (e.g., Chemical, Polymer, Protein).
ITIS TSN
180092
Taxonomic Serial Number for species identified in the Integrated Taxonomic Information System.
NCBI Taxonomy
9606
Unique numeric identifier used to specify biological species in the NCBI database.

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Sersacabtagene Autoleucel. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

SERSACABTAGENE AUTOLEUCEL

Common Names & Synonyms

AUTOLOGOUS CD4+/CD8+ ENRICHED T LYMPHOCYTES OBTAINED FROM PERIPHERAL BLOOD LYMPHOCYTES BY LEUKAPHERESIS, TRANSDUCED WITH A SELF-INACTIVATING LENTIVIRAL VECTOR ENCODING A HUMANIZED CHIMERIC ANTIGEN RECEPTOR (CAR) TARGETING CD20 THAT INCLUDES A CD8.ALPHA. SIGNALLING PEPTIDE, AN ANTI-CD20 SINGLE CHAIN VARIABLE FRAGMENT (SCFV) DERIVED FROM HUMAN MONOCLONAL IGG1 KAPPA ANTIBODY OFATUMUMAB, AN IGG4 HINGE REGION, CD8 TRANSMEMBRANE REGION, AND AN INTRACELLULAR 4-1BB CO-STIMULATORY AND CD3.ZETA. SIGNALLING DOMAIN UNDER CONTROL OF THE ELONGATION FACTOR 1 ALPHA (EF-1.ALPHA.) PROMOTER AND A WOODCHUCK HEPATITIS VIRUS POSTTRANSCRIPTIONAL REGULATORY ELEMENT (WPRE). THE VECTOR ALSO CONTAINS AN HIV-1 PACKAGING SIGNAL (.PSI.), GAG, REV RESPONSE ELEMENT (RRE), CENTRAL POLYPURINE TRACT AND CENTRAL TERMINATION SEQUENCE (CPPT/CTS), IS FLANKED BY 5' AND 3' LONG TERMINAL REPEATS (LTRS) AND IS PSEUDOTYPED BY THE VESICULAR STOMATITIS VIRUS (VSV) G GLYCOPROTEIN.
SERSACABTAGENE AUTOLEUCEL [INN]

External Clinical & Regulatory Resources

NCATS
Inxight Drugs
NLM
DailyMed Products
NCATS
GSRS Full Record
NIH
NCI Thesaurus