SURZEBICLIMAB
UNII 53YMC3A1CU

Substance Identification & Data

This profile provides standardized clinical and technical data for Surzebiclimab, uniquely identified by the FDA Unique Ingredient Identifier (UNII) 53YMC3A1CU.

Technical mappings include the Chemical Abstracts Service (CAS) Registry Number 2342597-90-2 and the RxNorm Concept ID (RxCUI) N/A. Explore the sections below for detailed nomenclature and a complete directory of NDC-listed products containing this ingredient.

FDA UNII Code

53YMC3A1CU

CAS Registry Number

2342597-90-2

RxNorm Concept ID

N/A

Detailed Substance Profile

Preferred Name

SURZEBICLIMAB

Official standardized name for this substance within the FDA UNII nomenclature system.

NCI Thesaurus

C157242

National Cancer Institute reference terminology for clinical and research data.

INN ID

11453

Sequential identifier assigned via the WHO International Nonproprietary Name program.

USAN ID

KL-130

Identifier assigned by the United States Adopted Names Council.

Substance Type

protein

ISO 11238 classification category (e.g., Chemical, Polymer, Protein).

Synonyms and Nomenclature

This section provides a complete list of nomenclature and identifier mappings for Surzebiclimab. Identifiers are organized into official regulatory terms, commercial trade names, and technical systematic synonyms used to ensure accurate identification across clinical pharmaceutical databases, regulatory filings, and electronic health records.

FDA Official Name

SURZEBICLIMAB

Common Names & Synonyms

ANTI-TIM-3 MONOCLONAL ANTIBODY BGB-A425

IMMUNOGLOBULIN G1 (235-PROLINE,236-ALANINE,237-ALANINE,DE-239-GLYCINE,331-ALANINE), ANTI-(HUMAN HEPATITIS A VIRUS CELLULAR RECEPTOR 2) (HUMAN-MUS MUSCULUS MONOCLONAL BGB-A425 .GAMMA.1-CHAIN), DISULFIDE WITH HUMAN-MUS MUSCULUS MONOCLONAL BGB-A425 .KAPPA.-CHAIN, DIMER

IMMUNOGLOBULIN G1-KAPPA, ANTI-(HOMO SAPIENS HAVCR2 (HEPATITIS A VIRUS CELLULAR RECEPTOR 2, T-CELL IMMUNOGLOBULIN MUCIN FAMILY MEMBER 3, TIM-3, TIM3, TIMD3, CD366)), MONOCLONAL ANTIBODY; GAMMA1 HEAVY CHAIN (1-448) (VH (HOMO SAPIENS IGHV3-23*04 (93.8%) -(IGHD) -IGHJ4*01 (100%)) CDR-IMGT (8.7.13) (26-33.51-57.96-108) (1-119) -HOMO SAPIENS IGHG1*01, G1M17,1, G1V4 CH2 A114 (CH1 K120 (217) (120-217), HINGE 1-15 (218-232), LINKER (233-237), CH2 P114>A (330) (238-341), CH3 D12 (357), L14 (359) (342-446), CHS (447-448)) (120-448)), (222-218')-DISULFIDE WITH KAPPA LIGHT CHAIN (1'-218') (V-KAPPA (HOMO SAPIENS IGKV3-15*01 (84%) -IGKJ4*01 (100%)) CDR-IMGT (10.3.9) (27-36.54-56.93-101) (1'-111') -HOMO SAPIENS IGKC*01 (100%) KM3 A45.1 (157), V101 (195) (112'-218')); DIMER (228-228'':231-231'')-BISDISULFIDE, PRODUCED IN CHINESE HAMSTER OVARY (CHO) CELLS, GLYCOFORM ALFA

SURZEBICLIMAB [INN]

SURZEBICLIMAB [USAN]

SURZEBICLIMAB [WHO-DD]